脓毒症相关性急性肾损伤的危险因素分析  

Analysis of Risk Factors for Sepsis-Associated Acute Kidney Injury

作　　者：肖涛[1] 吴锡平[1] 关云艳[1] 王倩[1] 沈丽娟[1] 王亮[1] XIAO Tao;WU Xiping;GUAN Yunyan;WANG Qian;SHEN Lijuan;WANG Liang(Intensive Care Unit,Wuxi Traditional Chinese Medical Hospital,Wuxi 214071,China)

机构地区：[1]无锡市中医医院重症医学科,江苏无锡214071

出　　处：《医学综述》2018年第20期4133-4136,共4页Medical Recapitulate

摘　　要：目的分析脓毒症相关性急性肾损伤(AKI)的危险因素。方法回顾性分析2014年1月至2017年12月无锡市中医医院重症医学科收治的206例脓毒症患者的临床资料,记录患者的伴随疾病、实验室检查及急性生理和慢性健康评分Ⅱ(APACHEⅡ评分)、序贯器官功能衰竭评分(SOFA评分)、乳酸清除率,然后分析这些参数与脓毒症相关性AKI发生的相关性。结果脓毒症相关性AKI的发生率为55. 34%(114/206),肥胖(OR=2. 491,95%CI 1. 280～4. 850,P=0. 007)、糖尿病(OR=2. 022,95%CI 1. 042～3. 921,P=0. 037)、血小板减少(OR=2. 415,95%CI 1. 210～4. 819,P=0. 012)是脓毒症相关性AKI的危险因素。结论糖尿病、肥胖和血小板减少是脓毒症患者并发AKI的危险因素。Objective To analyze the risk factors for sepsis-associated acute kidney injury-（SA-AKI）. Methods Medical records of 206 sepsis patientsin ICU of Wuxi Traditional Chinese Medical Hospital between Jan. 2014 and Dee. 2017 were retrospectively analyzed. We investigated the eomorbidities, laboratory- examination, acute physiology and chronic health evaluation Ⅱ （ APACHE Ⅱ ） score, sequential organ failure assessment （SOFA） score and lactic acid scavenging rate. The relationship between the parameters and incidence of SA-AKI was analyzed. Results AKI occurred in 114 patients （55.34%）. Obesity（ OR = 2. 491,95% CI 1. 280-4. 850, P = 0. 007 ）, diabetes mellitus （ OR = 2. 022,95% CI 1. 042-3. 921 ,P = 0.037） , thromboeytopenia（ OR = 2. 415,95 % CI 1.210-4.819, P = 0.012） were significantly associated with AKI in sepsis patients. Conclusion Diabetes mellitus, obesity and thromboeytopenia are risk factors for SA-AKI.

关 键 词：脓毒症相关性急性肾损伤 脓毒症 危险因素 

分 类 号：R631[医药卫生—外科学]