低T3综合征对急性心肌梗死患者预后的影响  

Effect of low T3 syndrome on the prognoses of patients with acute myocardial infarction

作　　者：何东旭[1] 田春阳[1] 宋佳[1] 温宗玉 武佳科 于彤彤[1] 焦云娣[1] 孙志军[1] 孙兆青[1] HE Dongxu;TIAN Chunyang;SONG Jia;WEN Zongyu;WU Jiake;YU Tongtong;JIAO Yundi;SUN Zhijun;SUN Zhao-qing(Department of Cardiology,Affiliated Shen~ing Hospital of China Mediccal University,Shenyang,Liaoning 110004,China)

机构地区：[1]中国医科大学附属盛京医院心内科

出　　处：《中国动脉硬化杂志》2018年第9期931-935,共5页Chinese Journal of Arteriosclerosis

基　　金：辽宁省科技厅社会发展攻关计划项目(2011225020)

摘　　要：目的了解低T3综合征对行经皮冠状动脉介入治疗（PCI）的急性心肌梗死患者预后的影响。方法收集2010年1月1日到2014年10月31日期间在盛京医院心内科确诊为急性心肌梗死的患者,入选行PCI的患者1604例,依据是否合并低T3综合征分为两组：低T3综合征组（n=107）和甲状腺功能正常组（n=1497）,收集患者的临床基本资料、冠状动脉造影及介入治疗结果、术后用药情况,记录终点事件,回顾性分析两组患者临床特点及预后差异。结果在随访期间,两组患者全因死亡率、心源性死亡率差异有统计学意义（P〈0.05）。COX分析显示,低T3综合征与全因死亡（HR=2.137,95%CI为1.039~4.393,P=0.039）和心源性死亡（HR=2.796,95%CI为1.379~5.669,P=0.004）独立相关。结论合并低T3综合征行PCI的急性心肌梗死患者具有更差的预后。Aim To study the effect of low T3 syndrome on the prognosis of patients with acute myocardial infarction undergoing percutaneous coronary intervention（PCI）. Methods From January 1,2010 to October 31,2014,1604 patients with acute myocardial infarction diagnosed in the Department of Cardiology of Shengjing Hospital were enrolled in this study. They were divided into two groups according to whether they were complicated with low T3 syndrome： low T3 syndrome group（n = 107） and normal thyroid function group（n = 1497）. Their general date,coronary angiographic data,PCI data,postoperative medication,and end-point events were recorded. The clinical characteristics and prognosis of the two groups were analyzed retrospectively. Results During the follow-up period,there were significant differences in all-cause mortality and cardiac mortality between the two groups（P〈0.05）. COX analysis showed that low T3 syndrome was independently associated with all-cause mortality（HR = 2.137,95% CI was 1.039 ~ 4.393,P = 0.039）and cardiac death（HR = 2.796,95%CI was 1.379 ~ 5.669,P = 0.004）. Conclusion Patients with acute myocardial infarction combined with low T3 syndrome undergoing PCI had worse prognosis.

关 键 词：低T3综合征 急性心肌梗死 经皮冠状动脉介入治疗 预后 

分 类 号：R541.4[医药卫生—心血管疾病]