创伤纤溶亢进的监测与抗纤溶治疗  

Monitoring of Hyperfibrinolysis in trauma and Antifibrinolysis Therapy

作　　者：宋景春[1] 方邦江 Song Jingchun;Fang Bangjiang(Intensive care unit,the 94th Hospital of PLA,Emergency and Critical Care Medicine Center of Nanjing Military Region,Najing,China;Hubei University of Chinese Medicine,Wuhan,China)

机构地区：[1]中国人民解放军第九四医院重症医学科南京军区急重症医学中心 [2]湖北中医药大学

出　　处：《实用休克杂志（中英文）》2018年第4期200-203,共4页Journal of Practical Shock

摘　　要：纤溶亢进是创伤性凝血病的重要病理生理过程，是创伤病人死亡的重要原因之一。严重创伤时出现纤溶亢进可导致止血块被迅速分解，进而造成创伤大出血而死亡。全血功能监测联合纤溶分子标志物可以对创伤时纤溶功能变化进行快速、准确的评估，并指导氨甲环酸进行抗纤溶治疗。Hyperfibrinolysis is an important pathophysiological process of traumatic coagulopathy and one of the important causes of death in traumatic patients. Hyperfibrinolysis in severe trauma can lead to rapid decomposition of hemostatic clots, resulting in massive hemorrhage and death. Whole blood function monitoring combined with fibrinolytic molecular markers can quickly and accurately assess the changes of fibrinolyric function during trauma and guide the antifibrinolytic treatment of tranexamic acid.

关 键 词：创伤 纤溶亢进 血栓弹力图 氨甲环酸 

分 类 号：R641[医药卫生—外科学]