深圳市流动人口耐多药结核病流行病学特征及治疗转归情况分析  

The epidemiological characteristics and treatment outcome of multi-drug resistant tuberculosis among migrating individuals in Shenzhen

作　　者：车晓玲[1] 吴清芳[1] 李明珍[1] 管红云[1] 谭卫国[1] CHE Xiao-ling;WU Qing fang;LI Ming-zhen;GUAN Hong-yun;TAN Wei-guo(Shenzhen Center for Chronic Disease Control,Shenzhen,Guangdong 518020,China)

机构地区：[1]深圳市慢性病防治中心,广东深圳518020

出　　处：《中国预防医学杂志》2018年第9期647-650,共4页Chinese Preventive Medicine

基　　金：中国全球基金结核病项目(CHN-506-G08-T);深圳市卫生计生系统科研项目(201506069)

摘　　要：目的分析深圳市流动人口耐多药结核病(multi-drug resistant tuberculosis,MDR-TB)流行病学特征及治疗转归情况。方法选取2012年1月至2016年12月,深圳市流动人口MDR-TB患者的流行病学特征、纳入治疗情况、治疗依从性评价及治疗转归情况等资料,计算MDR-TB患者的纳入治疗率、督导管理率及治疗成功率。结果 2012-2016年,深圳市检出确诊MDR-TB患者487例,其中流动人口451例(92.61%),以青壮年男性为主,职业主要为家政、家务及待业、原籍地以广东省(除深圳外)居多,128例(28.38%)。未纳入治疗231例(51.22%),其中返乡102例(44.16%);纳入项目进行治疗的患者有220例(48.78%),督导管理率88.64%(195/220);结案190例,成功治疗率68.42%(130/190)。结论由于采取综合防控措施,深圳市流动人口MDR-TB患者个案治疗取得了较好的效果。确诊患者纳入治疗情况不甚理想,需要继续优化耐多药结核病控制策略,加大对流动人口MDR-TB患者的纳入治疗力度,防止MDR-TB疫情蔓延。Objective To understand the epidemiological characteristics, treatment and outcome of multi-drug resistant tuberculosis （MDR-TB） among migrating individuals in Shenzhen. Methods Data of migrating in- dividuals with MDR-TB were collected in Shenzhen from January 2012 to December 2016, the epidemiological feature, disease treatment, treatment compliance, and disease outcome were analyzed. Results From 2012 to 2016, a total of 487 patients with MDR-TB were diagnosed and 451 （92.61%0） were migrating pa- tients. Most patients were young men, housekeepers and unemployed, with birth place of being Guangdong （28.38~）. 231 patients （51.22~） were untreated and 102 （44. 16%） went back their hometown. Only 220 patients were treated with the treatment rate of 48.78~. The disease management rate was 88.64~ （195/ 220）. Total 190 patients completed the treatment and 130 （68.42%） were successfully recovered. Conclu- sions Due to the comprehensive prevention and control measures, some of migrating individuals with MDR- TB are able to be well managed and treated. However, there are still some patients remained untreated, so more work has to be done to improve the treatment rate of migrating patients with MDR-TB in Shenzhen.

关 键 词：流动人口 耐多药 结核病 疾病管理 分析 

分 类 号：R521[医药卫生—内科学]