人工虫草类产品质量比较研究  

Quality Comparison Study of Cordyceps sinensis Originated from Different Cultivars

作　　者：刘旻虹 韦敏[2] 徐霞[2] 郑生智[2] 夏安扣 LIU Min-hong 2,WEI Min 2, XU Xia 2 et al(1.Changzhou Food and Drug Administration, Changzhou,Jiangsu 213002;2. Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014)

机构地区：[1]常州市食品药品监督检验中心,江苏常州213002 [2]江苏省中国科学院植物研究所,江苏南京210014 [3]溧阳市天目湖农业发展有限公司,江苏溧阳213300

出　　处：《安徽农业科学》2018年第31期170-172,共3页Journal of Anhui Agricultural Sciences

基　　金：常州市创新人才合作项目(CQ20164004)

摘　　要：[目的]对比研究不同人工虫草产品中有效物质含量。[方法]依照《中华人民共和国药典》(2015版)中的方法体系测定了人工虫草类产品的水分、灰分、浸出物含量;利用高碘酸钠比色法测定虫草酸;利用苯酚-硫酸法测定多糖;利用高效液相法测定腺苷、虫草素含量;国标法测定了蛋白、Ig G含量,同时以天然冬虫夏草作为对照。[结果]不同人工虫草中虫草酸、虫草素、腺苷及多糖,蛋白质和Ig G的含量均不同,其他虫草是否能替代冬虫夏草用于临床用药,还有待于进一步研究验证。[结论]该研究可为开发利用虫草的药用价值提供理论依据。[Objective]Comparative study on the content of effective substances of Cordyceps sinensis originated from different cultivars. [Method]Determination of moisture, ash and extract content according to the 2015 version of China Pharmacopoeia in the relevant provisions of the system;determination of the content of cordycepic acid by sodium periodate colorimetric method;determination of the content of polysaccharides by phenol sulfuric acid method;determination of the content of adenosine and cordycepin by HPLC;determination of the cordycepic acidontent of protein and IgG by national standard method. [Result]The contents of cordycepic acid, polysaccharide, adenosine and cordycepin, protein and IgG in different Cordyceps sinensis are different, and whether Cordyceps sinensis originated from other cultivars can replace Cordyceps sinensis for clinical use remains to be further studied and verified.[Conclusion]The study can provide theoretical basis for the development and utilization of medicinal value of Cordyceps sinensis .

关 键 词：虫草 质量控制 替代应用 

分 类 号：R282[医药卫生—中药学]