真性红细胞增多症与舞蹈症  

Polycythaemia vera and Chorea

作　　者：许力[1] 王春[1] 韦道祥[1] 李玉玉[1] 刘晓林[1] 屈洪党[1] 钱伟东[1] XU Li(Department of Neurology,the First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui,233004,China)

机构地区：[1]蚌埠医学院第一附属医院神经内科,安徽蚌埠233004

出　　处：《齐齐哈尔医学院学报》2018年第12期1486-1488,共3页Journal of Qiqihar Medical University

基　　金：安徽高校人文社会科学研究重点项目(SK2018A0181)

摘　　要：目的探讨真性红细胞增多症合并舞蹈症的发病机制、临床表现、鉴别诊断和治疗。方法报道以舞蹈症为首发症状的真性红细胞增多症2例,结合文献复习进行分析。结果 2例以舞蹈症为首发症状的JAK2基因突变阳性的真性红细胞增多症病例,有着不同的临床特征、影像学表现、疗效及预后,存在不同的发病机制。结论真性红细胞增多症合并舞蹈症是一种罕见综合征,按照不同的发病机制、临床特征、影像学表现、疗效及预后,可以分为两种类型:真性红细胞增多症舞蹈病及真性红细胞增多症性脑梗死舞蹈症,临床应注意区别。Objective To investigate the pathogenesis,clinical features,diagnosis and treatment effect of polycythemia vera combined with chorea. Methods Two cases of patients suffered polycythemia vera were enrolled in this study,with chorea as the first symptom,analyzed with literature review. Results We report the two cases of polycythemia vera those who with chorea as the first symptom and positive Janus Kinase-2（ JAK2）mutation,they were different in pathogenesis,clinical features,image study performance,curative effect and prognosis. Conclusions Polycythemia vera combined with chorea is a kind of rare syndrome. According to different pathogenesis,clinical features,image performance,curative effect and prognosis,polycythemia vera with chorea can be divided into two types： polycythemia vera chorea and polycythemia vera induced cerebral infarction chorea. We should pay attention to the difference of them in clinic.

关 键 词：舞蹈症 真红细胞增多症 真红细胞增多症舞蹈病 

分 类 号：R555[医药卫生—血液循环系统疾病]