肺结核咯血的治疗临床研究  

Clinical study the treatment of pulmonary tuberculosis hemoptysis

作　　者：鲁进 黄汉平[2] 谢亚梅 潘红梅 杜卫军 LU Jin;HUANG Uanpin;XIE Yamei;PAN Uongmei;DU Weijun(Infectious Department,Third Hospital of Ezhou City,Ezhou 436000,China;Tuberculosis Department,Wuhan Medical Treatment Center,Wuhan 430032,China)

机构地区：[1]湖北省鄂州市第三医院感染科,湖北鄂州436000 [2]武汉市医疗救治中心结核病科,湖北武汉430032

出　　处：《中国医药科学》2018年第19期237-240,共4页China Medicine And Pharmacy

摘　　要：目的对保守止血治疗未见好转且反复咯血肺结核的患者,在内科保守治疗的基础上,研究通过常规输注血小板是否有益于患者止血治疗。方法回顾性分析2014年1月～2015年1月某三级医院住院肺结核反复咯血患者80例,设继续临床内科止血用药的为对照组,在内科常规治疗的基础上通过输注血小板5～10单位(100～250mL)治疗的为观察组,各组40例,观察临床疗效及转归情况,按一周内咯血治愈,二周内咯血治愈,需介入干预处理三种情况分类收集资料,进行比较分析,同时对一周内咯血治愈人数情况与二周内咯血治愈人数情况进行统计分析。结果观察组一周内咯血治愈率(65.0%)明显高于对照组(40%),转归时间明显缩短,需介入干预处理人数明显少于对照组,明显提高治愈疗效,观察组与对照组对于咯血治愈转归比较中,差异有统计学意义(P <0.05),观察组与对照组对于一周内咯血患者治愈疗效比较差异有统计学意义(P <0.05),但在二周后咯血治愈疗效比较中差异无统计学意义(P> 0.05)。结论通过输注血小板治疗能有效提高反复咯血肺结核患者治疗转归,特别是在提高一周内治愈率,减少患者不必要的经济花费及住院疗程,减少发生咯血危重险情的概率,规避了可能的并发症及死亡风险,有益于肺结核反复咯血治疗。Objective On the basis of conservative treatment of internal medicine, to study whether the conventional infusion of platelets is beneficial to tuberculosis patients with conservative hemostasis treatment without improvement and repeated hemoptysis. Methods Eighty tuberculosis patients with repeated hemoptysis in the tertiary hospital from January 2014 to January 2015 were retrospectively analyzed. The patients who continued clinical medicine hemostasis medication were as the control group, on the basis of routine medical treatment, the patients who treated by infusion of platelets 5-10（100-250mL） were as the observation group, each group had 40 cases. The clinical efficacy and outcomes were observed. Hemoptysis was cured within one week, two weeks, and interventional intervention, collected data in this three cases to compare and analyze. At the same time, statistically analyzed the number of hemoptysis cured within one week and within two weeks. Results The cure rate of hemoptysis in the observation group within one week（26 cases, 65.0%） was significantly higher than that of the control group（16 cases, 40%）, the time of return is significantly shortened. The number of interventions required was significantly less than that of the control group, significantly improve the curative effect. There was a statistically significant difference between the observation group and the control group in hemoptysis cure outcome（P 〈 0.05）. There was a statistically significant difference between the two groups in the treatment of hemoptysis cured within one week（P 〈 0.05）, however, there was no significant difference in the efficacy of hemoptysis after two weeks（P 〉 0.05）. Conclusion Infusion of platelet therapy can effectively improve the treatment outcome of patients with repeated hemoptysis, especially in improving the cure rate within one week, reduce unnecessary economic costs and hospitalization, reduce the risk of hemoptysis, avoid possible complications and risk of death, it＇ s beneficial

关 键 词：肺结核 咯血 治疗 临床研究 

分 类 号：R521[医药卫生—内科学]