脱细胞基质材料生物补片在腹股沟疝修补术中的应用研究  

Study on the use of acellular tissue matrix in inguinal hernia repair

作　　者：孙中伟 李戈 孙少川 孟岩 Sun Zhongwei;Li Ge;Sun Shaochuan;Meng Yan(Department Gastrointestinal Surgery;Operating room,Jinan Central Hospital Affiliated Shandong University,Jinan 250013,China)

机构地区：[1]山东大学附属济南市中心医院胃肠外科,250013 [2]山东大学附属济南市中心医院手术室,250013

出　　处：《中华疝和腹壁外科杂志（电子版）》2018年第5期371-374,共4页Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition)

摘　　要：目的探讨脱细胞基质材料生物补片在腹股沟疝修补术的应用效果。方法回顾性分析2015年12月至2017年9月,山东大学附属济南市中心医院301例(372侧)腹股沟疝修补手术患者的临床资料。按照术中使用补片不同,分为2组。试验组患者117例(141侧),术中使用生物补片;对照组患者184例(231侧),术中使用合成补片。对照分析2组的疗效和并发症等的差异。结果在腹腔镜腹股沟疝修补术中试验组手术时间较对照组长,差异有统计学意义(P<0.01);2组感染、复发、慢性疼痛、浆液肿发生情况比较,差异无统计学意义(P>0.05)。开放疝修补中试验组和对照组手术时间、感染、复发、慢性疼痛、合成补片及浆液肿比较,差异均无统计学意义(P>0.05)。2组补片价格及异物感比较,差异有统计学意义(P<0.05);术后住院时间比较,差异无统计学意义(P>0.05)。结论脱细胞基质材料生物补片可以安全有效的修补疝环缺损<3cm的腹股沟疝,但是费用较高。Objective To explore the application effect of acellular tissue matrix patch in inguinal hernia repair. Methods Retrospectively analyze the data of 301 patients（372 sides） of inguinal hernia repair from December 2015 to October 2017 in Jinan Central Hospital Affiliated Shandong University. Then compare the efficacy and complications between acellular tissue matrix（n=141） and synthetic patch（n=231） in inguinal hernia repair. Results In laparoscopic inguinal hernia repair, operation time of using acellular tissue matrix was longer than that using synthetic patch, but there were no differences in infection, recurrence, chronic pain, seroma and postoperative hospitalization. In open hernia repair, there were no differences in the time of operation and postoperative hospitalization. One patient suffered infection and one recurrence in acellular tissue matrix group. 2 patients suffered chronic pain in synthetic patch group. Less foreign body sensation in the acellular tissue matrix group. Conclusion Acellular tissue matrix could be safely and effectively used to repair the inguinal hernia with defect less than 3 cm, but the cost is higher.

关 键 词：疝 腹股沟 疝修补术 脱细胞组织基质 

分 类 号：R656.21[医药卫生—外科学]