地奥司明联合α-受体阻滞剂治疗ⅢB型前列腺炎的疗效观察  

The curative effect observation of diosmin combined with α-blockers in the treatment of type Ⅲ B prostatitis

作　　者：王家菁[1] 杨盛[1] 陈永华[1] 张军[1] 刘佳[1] 赵纪宇 肖飞[1] 谷现恩[1] WANG Jia-jing;YANG Sheng;CHEN Yong-hua;ZHANG Jun;LIU Jia;ZHAO Ji-yu;XIAO Fei;GU Xian-en(Urology Center,Chuiyangliu Hospital Affiliated to Tsinghua University,Beijing 100022,China)

机构地区：[1]清华大学附属垂杨柳医院泌尿中心,100022

出　　处：《蚌埠医学院学报》2018年第9期1176-1178,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨地奥司明联合α-受体阻滞剂治疗ⅢB型前列腺炎的治疗效果。方法:选择200例ⅢB型前列腺炎病人,随机均分为2组,对照组仅用坦索罗辛治疗,观察组采用地奥司明联合α-受体阻滞剂坦索罗辛进行治疗,比较2组病人治疗前后慢性前列腺炎症状指数评分(NIH-CPSI)、国际勃起功能指数评分(IIEF-5)、生活质量评分(QOL)情况,对2组病人进行疗效评价并观察不良反应的发生情况。结果:治疗前,2组病人各项临床症状评分差异无统计学意义(P> 0. 05)。2组病人治疗后NIH-CPSI、QOL均较治疗前降低,IIEF-5评分较治疗前升高,且观察组病人治疗后的NIH-CPSI评分、QOL评分均低于对照组,IIEF-5评分高于对照组(P <0. 05～P <0. 01)。观察组总有效率达90%,高于对照组的70%(P <0. 05)。2组不良反应发生率差异无统计学意义(P> 0. 05)。结论:采用地奥司明联合坦索罗辛治疗ⅢB型前列腺炎能够显著改善病人的性功能,提高生活质量,治疗效果好,不良反应轻微。Objective： To investigate the clinical effects of diosmin combined with α-blockers in the treatment of type Ⅲ B prostatitis.Methods： Two hundred patients with type Ⅲ B prostatitis were randomly divided into the control group and observation group（100 cases each group）.The control group and observation group were treated with tamsulosin and diosmin combined with α-blockers,respectively.The chronic prostatitis index score（NIH-CPSI）,international index of erectile function score（IIEF-5） and quality of life score（QOL） between two groups before and after treatment were compared.The curative effects in two groups were evaluated,and the occurrence of adverse reactions in two groups were observed.Results： Before treatment,the differences of all item scores between two groups were not statistically significant（ P 〉0.05）.Compared with before treatment,the NIH-CPSI score and QOL score in two groups decreased,and the IIEF-5 score increased after treatment.After treatment,the NIH-CPSI score and QOL score in observation group were lower than those in control group,and the IIEF-5 score in observation group was higher than that in control group（ P 〈0.05 to P 〈 0.01 ）.The total effective rate in observation group（90%） was significantly higher than that in control group（70%）（ P 〈0.05）,and the difference of the incidence rate of adverse reactions between two groups was not statistically significant（ P 〉0.05）.Conclusions： Diosmin combined with tamsulosin in treating type Ⅲ B prostatitis can significantly improve the patient′s sexual function and quality of life,which has good effect and mild adverse reactions.

关 键 词：前列腺炎 地奥司明 Α-受体阻滞剂 

分 类 号：R697.33[医药卫生—泌尿科学]