黄山市两县区婴幼儿卡介苗接种效果的分析  

Effect of BCG vaccination in infants in two counties/districts of Huangshan City,Anhui Province,China

作　　者：张向阳[1] 骆卫群 杨静 ZHANG Xiang-yang;LUO Wei-qun;YANG Jing(The Center for Disease Control and Prevention of Huangshan City,Huangshan 245000,Anhui Province,China)

机构地区：[1]黄山市疾病预防控制中心,安徽黄山245000 [2]黄山市祁门县疾病预防控制中心,安徽黄山245600 [3]黄山市徽州区疾病预防控制中心,安徽黄山245061

出　　处：《中国生物制品学杂志》2018年第10期1122-1125,共4页Chinese Journal of Biologicals

摘　　要：目的分析黄山市祁门县及徽州区婴幼儿卡介苗(BCG)接种效果。方法对黄山市祁门县及徽州区两县区接种BCG 12周的婴幼儿进行BCG纯蛋白衍生物(purified protein derivatives of BCG,BCG-PPD)试验,并对试验结果进行统计学分析。结果黄山市两县区婴幼儿卡痕率99.03%、BCG-PPD阳性率89.37%。祁门县婴幼儿BCG-PPD阳性率(93.46%)明显高于徽州区(85.00%),城市婴幼儿BCG-PPD阳性率(95.19%)明显高于农村(83.50%),差异均有统计学意义(P<0.01);男性婴幼儿BCG-PPD试验阳性率(89.00%)与女性(89.72%)差异无统计学意义(P>0.05);两县区婴幼儿卡痕均径为4.32 mm,卡痕均径≥3 mm BCG-PPD阳性率(92.49%)明显高于卡痕均径<3 mm的阳性率(73.53%),差异有统计学意义(P<0.01);在城市二级以上医院产科接种室接种的婴幼儿的BCGPPD阳性率与各预防接种门诊差异无统计学意义(P>0.05)。结论黄山市两县区BCG接种质量总体较好,但存在城市与农村间接种质量不平衡现象;卡痕均径大小可作为BCG接种质量参考依据之一。Objective To analyze the effect of BCG vaccination in Qimen County and Huizhou District of Huangshan City, Anhui Province, China. Methods BCG-PPD test was performed on the infants in Qimen County and Huizhou District of Huangshan City 12 weeks after BCG vaccination, of which the result was analyzed statistically. Results The scar formation rate and BCG-PPD positive rate of infants in two counties / districts in Huangshan City were 99. 03% and 89. 37% respectively. The positive rate of BCG-PPD was significantly higher in Qimen （93.46%） than in Huizhou （85. 00%）, and in urban （95. 19%） than in rural area （83.50%） （each P 〈 0. 01）. However, the BCG-PPD positive rate in male infants （89. 00%） showed no significant difference with that in female ones （89. 72%）（P 〉 0. 05）. Both the average scar diameters in Qimen and Huizhou were 4. 32 mm. The BCG-PPD positive rate in infants with average scar diameters of not less than 3 mm was 92. 49%, which was significantly higher than that with average scar diameters of less than 3 mm （73. 53% ）（P 〈 0. 01 ）. However, the BCG-PPD positive rate of infants vaccinated in the obstetric wards of hospitals of not less than the second-class showed no significant difference with that in vaccination clinics （P 〉 0. 05）. Conclusion The qualities of BCG vaccination in the two counties / districts of Huangshan City were satisfactory in general. However, there was an imbalance between urban and rural areas. The average scar diameter might be served as one of the reference for BCG vaccination quality.

关 键 词：卡介苗 卡介苗纯蛋白衍生物试验 接种效果 

分 类 号：R378.91[医药卫生—病原生物学] R186.2[医药卫生—基础医学]