良性前列腺增生ESWAN成像与临床指标的对照研究  

Comparative Study of ESWAN Imaging and Clinical Indexes of Benign Prostate Hyperplasia

作　　者：辛建英[1] 邵显敏 高珊珊[1] 门永超 王锡臻[1] 孙西河[1] 王滨[2] 

机构地区：[1]潍坊医学院附属医院影像中心,潍坊261031 [2]滨州医学院

出　　处：《临床放射学杂志》2016年第2期238-242,共5页Journal of Clinical Radiology

基　　金：国家自然科学基金项目(编号:81171303;30470518);山东省自然科学基金项目(编号:ZR2009CL046;ZR2010HQ029);山东省优秀中青年科学家科研奖励基金项目(编号:BS2012YY038);山东省卫生厅科技发展项目(编号:2011WSB29009;2011HW067);滨州医学院山东省强化建设重点特色学科;山东省科技攻关项目(编号:2007GG30002032;2008GG30002004);潍坊医学院博士科研启动基金(2009)

摘　　要：目的对比分析良性前列腺增生（BPH）区及正常前列腺周围带（PZ）在多回波采集重度T2*加权三维梯度回波（ESWAN）序列上成像的特征,探讨多指标ESWAN评估BPH的可行性。方法对病理证实的48例BPH患者行ESWAN扫描,分别测量BPH和PZ的R2*值、T2*值、相位值及磁矩值,比较BPH和PZ、尿潴留组（15例）和非尿潴留组（23例）增生区ESWAN指标的差异。结果 BPH的R2*值、T2*值及磁矩值分别为20.16±3.04、50.41±8.53、1559.88±261.10,正常周围带的相应各值分别为16.15±8.45、80.96±56.86、1505.53±252.48;BPH的R2*值>PZ（P=0.006）,T2*值<PZ（P=0.000）,而磁矩值>PZ（P=0.023）。BPH的相位值<PZ,但两者差异不具统计学意义（P=0.294）。尿潴留组增生区R2*值（20.61±2.47）大于非尿潴留组（18.73±2.81）,且差异具有统计学意义（P=0.037）;尿潴留组增生区T2*值（50.13±4.85）小于非尿潴留组（56.88±8.63）,差异亦存在统计学意义（P=0.009）。两组相位值及磁矩值差异均不具有统计学意义（P>0.05）。结论 BPH与正常周围带在ESWAN上具有各自的特征性,R2*、T2*值对BPH合并尿潴留有临床诊断价值,有助于进一步扩展ESWAN在前列腺疾病中的应用。Objective To investigate the feasibility of using enhanced T_2~* star weighted angiography(ESWAN) in evaluating BPH by analyzing imaging characteristics of benign prostate hyperplasia(BPH) and normal prostate peripheral zone(PZ).Methods ESWAN was performed on forty eight patients with pathologically proved BPH.R_2~*,T_2~*,phase value and magnitude value of BPH and PZ were measured using GE ADW4.5 workstation.ESWAN indexes were analyzed using t-test.Results R_2~*,T_2~* and magnitude value of BPH were 20.16 ± 3.04、50.41 ± 8.53、1559.88 ± 261.10 respectively.The corresponding values of peripheral zone were 16.15 ±8.45,80.96 ±56.86,1505.53 ±252.48.R_2~* value in BPH was higher than PZ(P = 0.006),T_2~* value lower than PZ(P = 0.000),while magnitude value higher than PZ(P =0.023).The phase value of BPH was lower than PZ,but there was no statistical difference(P =0.294).R_2~* value of BPH in urinary retention group was higher than that in no urinary retention group(P =0.037),20.61 ±2.47 and 18.73±2.81 respectively.T_2~* value of BPH in urinary retention group was higher than that in no urinary retention group(P =0.009),50.13 ±4.85 and 56.88 ±8.63 respectively.The difference of magnitude value and phase value had no statistical significance between the two groups.Conclusion Imaging features were found between BPH and normal PZ on ESWAN,and R_2~*,T_2~* value has clinical diagnostic value for BPH with urinary retention,which indicates the potential value in the study of prostate diseases using ESWAN in future.

关 键 词：良性前列腺增生 磁共振成像 磁敏感加权成像 多回波采集T2*加权三维梯度回波 

分 类 号：R445.2[医药卫生—影像医学与核医学] R697.3[医药卫生—诊断学]