良性软骨母细胞瘤临床病理分析  

Clinical and Pathological Features of Benign Chondroblastoma

作　　者：熊小亮[1] 俞薇薇[1] 艾有生[1] 陈祈妹 张金先[3] 

机构地区：[1]江西医学院病理教研室,江西南昌330006 [2]广东省英德市人民医院病理科,广东英德513000 [3]江西省中医院放射科,江西南昌330006

出　　处：《实用临床医学（江西）》2001年第A02期15-17,共3页Practical Clinical Medicine

摘　　要：目的 :探讨良性软骨母细胞瘤的临床及病理特征。方法 :对 16例软骨母细胞瘤进行临床资料分析和组织病理学 ,免疫组织化学观察 ,并结合文献进行临床病理分析、讨论。结果 :该肿瘤多发生于青少年。主要发生在股骨、胫骨及肱骨。组织学特征 :肿瘤由软骨母细胞瘤和多核巨细胞组成 ,软骨细细胞间有软骨样基质并可窗格状钙化。免疫化结果为 :软骨母细胞表达Vimentin及S 10 0 ,巨细胞均为阴性。结论 :良性软骨母细胞瘤易误诊为骨巨细胞瘤 ,应结合临床表现。Object: To study the clinnical and pathological characteristics of Benign Chondroblastoma. Methods: Clinical, histopathological, and immunohistochemcal observation and analysis combined with the documents were done in 16 cases of benign chondroblastoma. Results: The tumors mainly occurred in adolescents and located in the Femur, tibia, and humerus. Histopathologically, the tumors were composed of chondroblast and multinucleated giant cell. There were cartilaginoid stroma and calcification as lattice appeared inter the chondroblasts. Immunohistochemically chondroblast expressed vimentin and S 100 protein, but multinucleated giant cell didn’t. Conclusion: This tumor is easily misdiagnosed as giant cell tumor of bone. The combination of clinical observation, X ray examination, and pathological examination is essential for the diagnosis of benign chondroblastoma.

关 键 词：良性软骨母细胞瘤 临床病例 病理学 

分 类 号：R4[医药卫生—临床医学]