同步换血治疗重症新生儿高间胆红素血症  

Application of Synchronous Exchange Transfusion in Treatment of Hyperbilirubinemia of Newborn

作　　者：王维琼[1] 杨华姿[1] 伍淑文[1] 

机构地区：[1]广东省中山市博爱医院,528402

出　　处：《实用临床医学（江西）》2001年第A02期35-36,共2页Practical Clinical Medicine

摘　　要：目的 :探讨同步换血对重症新生儿高间胆红素血症的疗效。方法 :对重症新生儿高间胆红素血症患儿采用脐静脉或桡动脉抽血与外周小静脉输血的同步换血法 ,并于换血前后进行血常规、生化、胆红素、血培养等检查。结果 :脐静脉或桡动脉与外周小静脉双管同步换血疗法 ,两者疗效无明显差异 (P >0 .0 5 ) ,均能在治疗 2 4h使血清胆红素浓度下降 >5 0 %。重症于 3d左右消退 ,未发生后遗症。结论 :采用双管同步换血疗法治疗重症新生儿高间接胆红素血症快速、安全、可靠 。Objective: To evaluate the therapeutic efficacy of synchronous exchange transfusion on hyperbilirubinemia. Methods: Hyperbilirubinemia of newborn was treated with synchronous exchange transfusion(umbilical vein or radial recurrent artery and peripheral vein). The patients underwent some examinations including blood routine, blood culture, biochemical test, and bilirubin assay. Results: There was no significant difference of the therapeutic efficacy between the two groups(P>0.05). Serum bilirubin levels of both groups lowed by 50% after 24 hours of treatment and returned to normal range after 3 days of treatment without any commemorative sign. Conclusion: It’s safe and should be carried out as soon as possible to use synchronous exchange transfusion for hyperbilirubinemia of newborn.

关 键 词：新生儿 重症高间胆红素血症 同步换血 

分 类 号：R4[医药卫生—临床医学]