钌催化烯烃复分解反应中的氢键效应  

Hydrogen-Bonding Effects in Ruthenium-Catalyzed Olefin Metathesis

作　　者：颜廷斌 刘跃辉 沈悦海[1] Yan Tingbin;Liu Yuehui;Shen Yuehai(Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming 65050)

机构地区：[1]昆明理工大学生命科学与技术学院,昆明650500

出　　处：《有机化学》2018年第10期2491-2500,共10页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21662022)资助项目~~

摘　　要：烯烃复分解反应是近二十年来最常用的合成方法之一.由于钌催化剂良好的官能团耐受性,氢键作用已成为烯烃复分解反应的重要控制因素.全面综述了氢键作用促进的钌催化烯烃复分解反应的历史发展和合成应用,并介绍了相关的反应机理研究.Olefin metathesis is among the most popular synthetic methods over the past two decades. Owing to the good functional group tolerance of ruthenium catalysts, hydrogen bonding has emerged as a powerful controlling element for olefin metathesis recently. Recent studies demonstrated that the hydrogen bonding between ruthenium catalyst and certain types of substrates or additives could significantly improve the rate, chemoselectivity and stereoselectivity of olefin metathesis, while the self-assembly of substrates could be driven by intramolecular or intermolecular hydrogen bonding and result in highly selective reactions. In this review, the development and application of hydrogen bonding-promoted ruthenium-catalyzed olefin metathesis reactions are summarized, and the mechanism insights into these systems are highlighted.

关 键 词：烯烃复分解 钌卡宾络合物 催化 氢键作用 

分 类 号：O621.251[理学—有机化学]