绝经后女性慢性肾脏病患者合并心力衰竭的相关研究进展  

Research progress of chronic kidney diseases in relation to heart failure among postmenopausal women

作　　者：刘云欢 侯原平[1] 常晶[1] 孙倩美[1] LIU Yun-Huan;HOU Yuan-Ping;CHANG Jing;SUN Qian-Mei(Integrated Department,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院综合科,北京100020

出　　处：《中华老年多器官疾病杂志》2018年第11期859-861,共3页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：北京市保健科研项目(京17-05);北京市科委首都市民健康培育项目(Z171100000417055);首都医科大学学生科研创新项目(XSKY2017139)~~

摘　　要：绝经后女性由于雌激素水平下降,心血管疾病的风险升高。慢性肾脏病(CKD)是随年龄增长发病率逐年上升的疾病之一,同样多见于绝经后的女性。若绝经后女性同时合并CKD将易出现心力衰竭(HF)。本文将从近年来临床及基础研究结果入手,深入分析绝经后女性CKD患者发生HF的相关机制,以期增进对绝经后女性CKD患者相关研究的了解,促进未来对该病新治疗靶点的识别与进一步研究。Postmenopausal women are at increased risk of cardiovascular diseases due to decreased estrogen levels. The prevalence of chronic kidney disease （CKD） increases with age, and the disease is common among postmenopausal women. Postmenopausal women with CKD are vulnerable for heart failure. In this review, based on the clinical trials and basic research, we focused on CKD in relation to the mechanism of heart failure among postmenopausal patients, aiming at a better understanding of the condition, and future orientation for further studies.

关 键 词：绝经后 女性 慢性肾脏病 心力衰竭 

分 类 号：R541[医药卫生—心血管疾病]