抗精神病药物诱导心脏功能损害的监测现状  

Monitoring Status of Cardiac Function Impairment Induced by Antipsychotic Drugs

作　　者：樊树华 苏勤 金星 姜敏 FAN Shuhua;SU Qin;JIN Xing;JIANG Min(Department of Ultrasound,Yibin Fourth People′s Hospital,Yibin 644002,China)

机构地区：[1]宜宾市第四人民医院超声科,四川宜宾644002

出　　处：《医学综述》2018年第21期4240-4244,共5页Medical Recapitulate

基　　金：宜宾市科技计划项目(2015SF037)

摘　　要：精神病患者药物治疗时间长,部分患者需终身服药,而抗精神病药物(APs)会诱导患者出现某些心血管疾病,但目前对APs诱导心脏功能损害的监测评价尚不充分。临床常见的监测方法有心电图检查、心肌酶监测、心脏彩色多普勒超声检查等,虽然每种方法均能从不同角度反映心脏功能的改变,但由于相关研究并不深入,故能为临床用药提供的参考价值有限。超声斑点追踪显像是近年开展的一种评价早期心脏功能损害的新技术,但其应用于服药精神病患者心脏功能监测的相关文献报道较少。未来,应对各种监测方法进行深入研究,以期为临床提供准确及时的APs诱导心脏功能损害程度的报道。Psychiatric patients need long-term medication,and some patients need to take drugs for life.However,antipsychotics（APs） can induce some cardiovascular diseases in patients,but the monitoring and evaluation of APs-induced cardiac damage is not sufficient at present.The common clinical monitoring methods include electrocardiogram,myocardial enzyme monitoring,cardiac color Doppler ultrasound examination,etc.Although each examination method can reflect the changes of cardiac function from different perspectives, the reference value for clinical medication is limited due to the lack of in-depth studies.Ultrasound speckle tracking imaging is a new technique developed in recent years to evaluate early cardiac function impairment,but its application in monitoring cardiac function in psychiatric patients with medication is rarely reported.In the future, various monitoring methods should be further studied in order to provide accurate and timely reports on the degree of APs-induced cardiac dysfunction.

关 键 词：抗精神病药物 心脏功能 监测 

分 类 号：R971[医药卫生—药品]