豚鼠听觉通路不同平面毁损的ABR频域分析  

Spectral Analysis of ABR with Destruction of Different Plane of Auditory Pathway in Guinea Pigs

作　　者：吴展元[1] 刘邦德[1] 黄治物 陆尔科 张道兰 

机构地区：[1]湖北医科大学附属第一医院耳鼻咽喉科,湖北咸宁医学院耳鼻咽喉科

出　　处：《听力学及言语疾病杂志》1995年第2期57-61,共5页Journal of Audiology and Speech Pathology

摘　　要：对１５只正常豚鼠的ＡＢＲ时域波形和频谱特征以及对１８只豚鼠通过脑干核团立体定位技术，毁损听觉通路各不同部位后的时域波形及频谱改变进行了分析。实验证明：正常豚鼠９０ｄＢＳＰＬ短声诱发的ＡＢＲ，呈现波Ⅰ、Ⅱ、Ⅲ、Ⅳ，通过平均功率谱分析，ＡＢＲ频谱范围在５０～２０００Ｈｚ，有３个谱能量集中区，ｆ０主峰中心频率为１８７．４７±２７．６８Ｈｚ，ｆ１为６９５．８２±１０３．４０Ｈｚ，ｆ２为１１０３．６７±８１．５５Ｈｚ。听觉通路不同部位毁损后，除影响一个时域主波形外，每个核团还不同程度地影响两个或两个以上波的形成。频谱图改变，有几个共同特点：（１）各谱峰中心频率向低频偏移；（２）谱分析带宽明显缩窄，高频截止区也向低频移动；（３）谱峰能量全面下降，甚至有的谱峰消失；（４）随毁损平面上行，谱能量损失减少，谱峰向低频区移动的程度降低。大多数核团对ｆ１有贡献，听神经及低位脑子对ｆ２的合成贡献较大，因此，应该认为ＡＢＲ频谱特征是整个听觉通路各部位的综合效应。An analysis was made of ABR frequency spectrum spectrum of 15 normal guinea pigs and 18 guinea pigs with the destruction of different plane of auditory pathway.The results indicated that the normal ABR spectral content was distributed around 50￣2000 Hz and characterized by three energy peaks:f0,f1 and f2.their frequencies being about 187,695 and 1103 Hz respectively.This study also demonstrated that a lesion of a single nuclus might affect not only a single component of the ABR,but also more typically on several other components.In the frequency domain analysis after destruction,there were several characteristics:(1)the positions of energy peaks moved to the low-frequency area;(2)the band of spectrum narrowed,i.e.the high cutoff frequency lowered;(3)decreasing in major peak energy,even some of peak;disappeared;(4)As the destroyed level rose,the degree of above changes fell.In addition, most of brain stem nuclei of auditory pathway made contribution to f1 and theⅧ th nerve and the nuclei of lower brain stem made more contributions to f2.Then it was considered that all sites in the brain stem auditory pathway had complex effects on the ABR frequency spectrum characteristics.

关 键 词：谱分析 听性脑干反应 核团 听觉通路 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]