化疗并发症预警模型在乳腺癌患者中的应用研究  

The effects of alert system for chemotherapy adverse events among breast cancer patients

作　　者：李旭英 谌永毅 石汉平[2] 路潜[3] 王可 李星凤 李金花 胡美华 林小平 魏涛 谭艳 LI Xuying;CHEN Yongyi;SHI Hanping;LU Qian;WANG Ke;LI Xingfeng;LI Jinhua;HU Meihua;LIN Xiaoping;WEI Tao;TAN Yan

机构地区：[1]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院护理部,长沙市410013 [2]中国医科大学航空总医院/中国科学院北京转化医学研究院肿瘤医学中心 [3]北京大学护理学院 [4]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院结直肠外科,长沙市410013 [5]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院乳腺内科,长沙市410013 [6]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院消化泌尿内科,长沙市410013 [7]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院胸部内科,长沙市410013

出　　处：《中华护理杂志》2018年第11期1338-1342,共5页Chinese Journal of Nursing

基　　金：恶性肿瘤姑息治疗和护理关键技术研究重大专项(ZDZX2017ZL-04-HN);湖南省科卫联合基金项目(2018JJ6111)

摘　　要：目的探讨化疗并发症预警模型在乳腺癌患者中的应用效果。方法 2017年6月—12月,将某三级甲等医院乳腺内科接受化疗的乳腺癌患者随机分为试验组和对照组,每组各60例。试验组在出院时、出院后2周通过手机APP进行化疗并发症及相关知识的指导,对照组行常规的电话随访指导及咨询服务,对比两组在化疗并发症、生活质量方面的差异。结果两组白细胞减少、血小板减少及恶心、呕吐发生率和生活质量总得分及各维度得分比较,差异有统计学意义(P<0.05),两组腹泻、便秘发生率比较,差异无统计学意义(P>0.05)。结论应用化疗并发症预警模型对乳腺癌患者化疗并发症进行监控及管理,能降低其化疗并发症发生率,提高其生活质量。Objective To explore the effects of alert system for chemotherapy adverse events among breast cancer patients. Methods From June 2017 to December 2017,breast cancer patients receiving chemotherapy from a tertiary hospital were recruited and assigned into the intervention group and the control group with 60 cases in each group. Patients in the intervention group received guidance regarding complications of chemotherapy and rele-vant knowledge via mobile APP at discharge and 2 weeks after discharge. Patients in the control group received routine telephone follow-up and consultation services. Differences between two groups in complications of chemotherapy and quality of life were compared. Results Two weeks after discharge,there were significant differences in leucocyte count,platelet count,nausea and vomiting between two groups（P〈0.05）,and no differences in diarrhea and constipation between two groups（P〉0.05）. Patients in the intervention group had higher scores of physical health,social support,emotional support,functional condition,and quality of life than the control group （P〈O.05）. Conclusion Implementation of alert system for chemotherapy adverse events among breast cancer patients can reduce the incidence of chemotherapy complications and improve their quality of life.

关 键 词：化疗并发症 预警 乳腺癌 

分 类 号：R473.73[医药卫生—护理学]