CFL2基因研究进展  

Advances in Research on CFL2 Gene

作　　者：赵拴平[1] 贾玉堂[1] 徐磊[1] 金海 Zhao Shuanping;Jia Yutang;Xu Lei;Jin Hai(Anhui Key Laboratory of Livestock and Poultry Product Safety Engineering,Institute of Animal Husbandry and Veterinary Medicine,Anhui Academy of Agricultural Science,Hefei 230031,China)

机构地区：[1]安徽省农业科学院畜牧兽医研究所畜禽产品安全工程安徽省重点实验室,合肥230031

出　　处：《中国草食动物科学》2018年第6期46-48,74,共4页China Herbivore Science

基　　金：国家肉牛产业技术体系-合肥综合试验站(CARS-37);安徽省科技攻关项目(1501031089);安徽省农业科学院院长青年创新基金项目(17B0408)

摘　　要：CFL2基因是肌动蛋白结合蛋白家族的重要成员,研究发现,CFL2基因主要在哺乳动物的骨骼肌和心肌中表达,在肌肉组织肌原纤维发生和解聚过程中调节肌动蛋白的转换,对维持肌肉正常的生长发育和功能起着非常重要的作用。文章总结了CFL2基因结构、表达特性及其在细胞增殖、凋亡、迁移和侵袭以及家畜经济性状(生长性状和肉质性状)中的重要作用,以期为进一步提高家畜养殖的经济效益以及育种改良寻求有效途径。CFL2（Cofilin 2） gene is one member of the actin binding protein family. Research indicated that CFL2 mRNA mainly expressed in mammalian skeletal muscle and cardiac muscle,and played an important role in muscle development and maintaince via regulating the conversion of actin in the process of myofibrils depolymerization. This article comprehensively analyzed the structure and expressional characteristic of CFL2 gene,and summarized its role in the cell proliferation,apoptosis,migration and invasion,the economic traits including growth and muscle traits of livestock were also summarized,in order to improve livestock economic benefits and provide new ideas for animal breeding.

关 键 词：CFL2 生长性状 肉质性状 家畜养殖 育种改良 

分 类 号：Q71[生物学—分子生物学]