艾司奥美拉唑在肝胆外科围术期的合理应用分析  

Analysis on rational application of esomeprazole for injection in hepatobiliary perioperative period

作　　者：钱跹 成丹 陈安妮[1] 张国庆[1] 战旗[1] QIAN Xian, CHENG Dan, CHEN Anni ,ZHANG Guoqing , ZHAN Qi(Department of Pharmacy , Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China)

机构地区：[1]上海东方肝胆外科医院药材科,上海200438

出　　处：《药学实践杂志》2018年第6期557-560,共4页Journal of Pharmaceutical Practice

基　　金：北京医卫健康公益基金会(编号:YWJKJJHKYJJA707)

摘　　要：目的了解东方肝胆外科医院(简称"我院")注射用艾司奥美拉唑钠在肝胆外科围术期应用的合理性,为肝胆手术围术期合理用药提供参考。方法用回顾性研究方法,通过查阅电子病历、医嘱和检验结果等途径,随机采集了2017年1月至9月300例使用注射用艾司奥美拉唑钠患者的相关信息。300例病例艾司奥美拉唑的使用频次为416次,从给药时间、用药疗程、用法用量、溶剂和应激性溃疡危险因素等方面进行分析。结果给药时间的合理率是15.67%(47/300),用药疗程的合理率是10.67%(32/300),用法的合理率是75%(312/416),用量的合理率是100%(416/416),溶媒的合理率为100%(416/416),具有应激性溃疡危险因素的患者占3.33%(10/300)。结论我院肝胆外科围术期应用艾司奥美拉唑合理性有待提高,临床药师应加强临床用药教育以提高合理用药水平。Objective To investigate the rationality of esomeprazole for injection in hepatobiliary perioperative period of Eastern Hepatobiliary hospital（hereinafter referred to as our hospital）,and to provide reference for the rational drug use in hepatobiliary perioperative.Methods By retrospective investigation,information of 300 randomly patients was collected from Jan to Sep in 2017 with esomeprezole for injection through consulting the electronic medical records,doctor’s advice,inspection,etc.Of the 300 cases of medical records with esomeprazole for injection,the use frequency of esomeprazole were 416,statistical analysis was conducted in terms of the administration time,treatment course,usage and dosage,solvent,and the risk of stress ulcer.Results The rational rate of the administration time was 15.67%（47/300）,the treatment course was 10.67%（32/300）,the usage was 75%（312/416）,dosage and solvent were 100%（416/416）,and the ratio of patients with SU risk factors was 3.33%（10/300）.Conclusion The rational application of esomeprezole in our hospital still need to be improved.The clinical pharmacists should strengthen clinical medicine education to improve rational drug use in our hospital.

关 键 词：艾司奥美拉唑 围手术期 临床用药指征 

分 类 号：R969[医药卫生—药理学]