女性生理事件与寻常性银屑病病情变化的相关性调查分析  

Investigative study on the correlation between female physiological events and disease severity in women with psoriasis vulgaris

作　　者：刘茜[1] 王璐[1] 朱冠男[1] 李彩霞[1] 王刚[1] LIU Qian;WANG Lu;ZHU Guan-nan(Department of Dermatology,Xijing Hospital,the Fourth Military Medical University,Xi＇an 710032,China)

机构地区：[1]第四军医大学西京皮肤医院,西安710032

出　　处：《实用皮肤病学杂志》2018年第5期279-281,共3页Journal of Practical Dermatology

摘　　要：目的调查分析女性生理事件与寻常性银屑病病情的关系。方法通过对300例女性寻常性银屑病患者进行回顾性问卷调查,了解女性生理事件(月经、妊娠、绝经)与寻常性银屑病病情变化之间的关系。结果 300例女性寻常性银屑病患者的月经、妊娠、绝经在女性的不同时期对寻常性银屑病的病情变化均有影响,31例(10.33%)患者自诉病情可在每次月经期加重,无患者报告病情减轻;在有妊娠史的201例患者中,68例(33.83%)患者自诉妊娠与寻常性银屑病病情变化有关,其中56例(82.35%)病情改善,12例(17.65%)加重;在绝经过渡期和绝经后期的98例患者中,40例(40.82%)患者自诉病情加重,无病情减轻患者。结论部分女性寻常性银屑病患者的病情与生理事件有关。Objective To investigate the correlation between female physiological events and disease severity in women with psoriasis vulgaris. Methods The correlation between female physiological events（defined as menstruation, pregnancy and menopause） was determined by retrospective analysis of questionnaires filled by 300 women with psoriasis vulgaris. Results In 300 enrolled women with psoriasis vulgaris, the impact of menstruation, pregnancy or menopause on psoriatic severity was found. Among the respondents, 31 women（10.33%） complained disease exacerbation during menstruation, none reported disease alleviation. Among 201 patients with history of pregnancy, 68（33.83%） patients reported that their condition changed during pregnancy, among which 56（82.35%） cases improved and 12（17.65%） cases worsened. Among 98 patients in the period of transition to menopause, 40（40.82%） cases reported disease exacerbation and no one reported alleviation. Conclusion In a proportion of woman subjects, severity of psoriasis vulgaris was correlated with female physiological events.

关 键 词：银屑病 寻常性 月经 妊娠 绝经 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]