杏黄止咳合剂联合复方甲氧那明胶囊治疗风热犯肺型感染后咳嗽临床研究  

Clinical Study on Xinghuang Zhike Mixture Combined with Compound Methoxyphenamine Capsules for Postinfectious Cough of Wind-heat Invading the Lung Type

作　　者：李艳[1] 郭明强 俞国美 嵇冰[1] LI Yan;GUO Mingqiang;YU Guomei;JI Bing

机构地区：[1]浙江中医药大学附属湖州市中医院,浙江湖州313000

出　　处：《新中医》2018年第11期78-81,共4页New Chinese Medicine

基　　金：国家自然科学基金项目(81403374)

摘　　要：目的:观察杏黄止咳合剂联合复方甲氧那明胶囊治疗风热犯肺型感染后咳嗽(PIC)的临床疗效。方法:将80例风热犯肺型PIC患者随机分成对照组和观察组,每组40例。对照组予口服复方甲氧那明胶囊,观察组在对照组基础上加用杏黄止咳合剂。比较2组治疗前后症状积分、愈显率及不良反应发生情况。结果:治疗后,2组咳嗽、咯痰、咽痒、口干、鼻燥积分及症状总积分均较治疗前降低,差异均有统计学意义(P <0.01);观察组主症、次症及症状总积分均低于对照组,差异均有统计学意义(P <0.05,P <0.01)。观察组愈显率70.0%,对照组愈显率32.5%,2组愈显率比较,差异有统计学意义(P <0.01)。治疗期间2组均未见不良反应。结论:杏黄止咳合剂联合复方甲氧那明胶囊治疗风热犯肺型PIC,效果优于单用复方甲氧那明胶囊。Objective： To observe the clinical effect of Xinghuang Zhike mixture combined with compound methoxyphenamine capsules for postinfectious cough （PIC） of wind-heat invading the lung type. Methods： Divided 80 cases of patients with PIC of wind-heat invading the lung type into the control group and the observation group randomly, 40 cases in each group. The control group was treated with compound methoxyphenamine capsules, while the observation group was additionally treated with Xinghuang Zhike mixture based on the treatment of the control group. Compared the symptom scores, cured and markedly effective rate and adverse reactions before and after treatment in the two groups. Results： After treatment, scores of cough, expectoration, tching throat, dry mouth, dry nose and total symptom scores were decreased in the two groups when compared with those before treatment, differences being significant （P 〈 0.01）. The scores of five symptoms and the total symptom score in the observation group were lower than those in the control group, differences being significant（P 〈 0.05, P〈0.01）. The cured and markedly effective rate was 70.0% in the observation group and 32.5% in the control group, the difference being significant （P 〈 0.01）. No adverse reactions were found in both groups during the treatment. Conclusion： The therapy of Xinghuang Zhike mixture combined with compound methoxyphenamine capsules has better therapeutic effect than that of simple compound methoxyphenamine capsules in treating patients with PIC of wind-heat invading the lung type.

关 键 词：感染后咳嗽(PIC) 风热犯肺型 中西医结合疗法 杏黄止咳合剂 复方甲氧那明胶囊 症状积分 疗效 

分 类 号：R56[医药卫生—呼吸系统]