降糖活络丸联合中药熏洗治疗2型糖尿病周围神经病变临床观察  

Clinical Observation of Jiangtang Huoluo Pills Combined with Chinese Herbal Fumigation and Washing for Peripheral Neuropathy Due to Type Ⅱ Diabetes

作　　者：颜国富[1] 杜亮亮[1] 李淑君[1] 曾豆云 YAN Guofu;DU Liangliang;LI Shujun;ZENG Douyun

机构地区：[1]岳阳市中医院,湖南岳阳414000

出　　处：《新中医》2018年第11期112-115,共4页New Chinese Medicine

基　　金：湖南省中医药管理局资助重点项目(201605)

摘　　要：目的:观察降糖活络丸联合中药熏洗治疗糖尿病周围神经病变的临床疗效。方法:将120例2型糖尿病周围神经病变患者分为3组,每组40例。降糖活络丸联合中药熏洗组(A组)在降糖活络丸组的基础上加中药熏洗治疗,降糖活络丸组(B组)在基础治疗上加用降糖活络丸治疗,对照组(C组)在基础治疗上加用甲钴胺治疗,均治疗4周后观察疗效,并比较3组治疗前后正中神经、腓总神经的感觉传导速度(SNCV)及运动神经传导速度(MNCV)的变化情况。结果:总有效率A组为92.5%,B组为75.0%,C组为60.0%;总有效率A组与B、C组比较,差异均有统计学意义(P <0.05);B组与C组比较,差异亦有统计学意义(P <0.05)。治疗后3组中医证候积分均较治疗前降低(P <0.05);且A组积分下降最显著,与B、C组比较,差异有统计学意义(P <0.05);B组积分下降亦较C组显著(P <0.05)。治疗后3组正中神经、腓总神经MNCV及SNCV均较治疗前升高(P <0.05)。A组正中神经MNCV值改善较B组更显著(P <0.05);A正中神经、腓总神经MNCV及SNCV值升高较C组更显著(P <0.05)。B组腓总神经MNCV值及正中神经、腓总神经SNCV值改善较C组更显著(P <0.05)。结论:在常规治疗的基础上,加用降糖活络丸联合中药熏洗及甲钴胺治疗糖尿病周围神经病变,可显著改善患者的症状,促进神经传导功能恢复,临床疗效显著。Objective： To observe the clinical effect of Jiangtang Huoluo pills combined with Chinese herbal fumigation and washing for peripheral neuropathy due to type II diabetes. Methods： Divided 120 cases of patients with peripheral neuropathy due to type II diabetes into three groups randomly, 40 cases in each group. The group of Jiangtang Huoluo pills combined with Chinese herbal fumigation and washing（group A）additionally received Chinese herbal fumigation and washing based on the treatment for the Jiangtang Huoluo pill group（group B）, the group B additionally received Jiangtang Huoluo pills based on the basic treatment, and the control group（group C）additionally received mecobalamin based on the basic treatment. The course of treatment for both groups lasted for 4 weeks. Observed the clinical effect, and compared the changes of sensory nerve conduction velocity（SNCV） and motor nerve conduction velocity（MNCV） in the median nerve and common peroneal nerve of the three groups before and after treatment. Results： The total effective rate was 92.5% in the group A, 75.0% in the group B and 60.0% in the group C; comparing the total effective rate in the group A with that in the group B and C respectively, there were significant differences being found（P 〈 0.05）; comparing the total effective rate in the group B with that in the group C, there was also significant difference being found（P 〈 0.05）. After treatment, Chinese medicine syndrome scores in the three groups were all lower than those before treatment（P 〈 0.05）; scores in the group A were decreased the most significantly, and when comparing with the group B and C, there was significant difference being found（P 〈 0.05）; scores in the group B were decreased more significantly than those in the groups C（P 〈 0.05）. After treatment, indexes of SNCV and MNCV in the median nerve and common peroneal nerve of the three groups were higher than those before treatment（P 〈 0.05）. The index of MNCV in the median nerve o

关 键 词：糖尿病周围神经病变 降糖活络丸 中药熏洗 

分 类 号：R587.2[医药卫生—内分泌]