清心滋肾健脾方治疗子宫切除术后卵巢储备功能下降临床观察  

Clinical Observation on Qingxin Zishen Jianpi Prescription for Patients with Diminished Ovarian Reserve After Hysterectomy

作　　者：刘海红[1] LIU Haihong

机构地区：[1]南通市中医院,江苏南通226000

出　　处：《新中医》2018年第11期141-142,共2页New Chinese Medicine

摘　　要：目的:观察清心滋肾健脾方对绝经前患者子宫切除术后卵巢功能的修复作用。方法:将绝经前行腹腔镜下次全子宫切除术或腹腔镜全子宫切除术者60例随机分为2组各30例。观察组于术后7天开始服用清心滋肾健脾方至术后3月,对照组术后不服用任何相关药物。观察比较2组术后3月及术后1年围绝经期症状、血清雌二醇(E)_2)、促黄体生成素(LH)及促卵泡激素(FSH)情况。结果:术后3月及术后1年,观察组改良Kupperman评分、E_2、FSH、LH分别与对照组比较,差异均有统计学意义(P <0.05)。观察组优于对照组。结论:清心滋肾健脾方可有效缓解围绝经期症状体征,延缓绝经前患者行子宫切除术后卵巢功能衰退的进程,且安全性好。Objective： To observe the repair effect of Qingxin Zishen Jianpi prescription on the ovarian function in premenopausal patients after hysterectomy. Methods： Divided 60 cases of premenopausal patients who had subtotal laparoscopic hysterectomy or total laparoscopic hysterectomy into two groups randomly, 30 cases in each group. On the 7th day after operation, the observation group began to take Qingxin Zishen Jianpi prescription until 3 months after operation, while the control group did not take any relevant medicines after operation. Observed and compared the perimenopausal symptoms and levels of serum estradiol （E2）, luteinizing hormone （LH） and follicle-stimulating hormone （FSH） in the two groups on the 3rd month and the 1st year after operation. Results： On the 3^rd month and the 1st year after operation, compared the modified Kupperman scores and levels of E2, FSH and LH in the observation group with those in the control group, differences were significant （P 〈 0.05）. The observation group was superior to the control group. Conclusion： Qingxin Zishen Jianpi prescription can effectively relieve the symptoms and signs of perimenopausal period, and delay the process of the decline of ovarian function in premenopausal patients after the hysterectomy, with good safety.

关 键 词：子宫切除术后 卵巢储备功能 清心滋肾健脾方 改良Kupperman评分 雌二醇(E_2) 促卵泡激素(FSH) 促黄体生成素(LH) 

分 类 号：R711.75[医药卫生—妇产科学]