产前及输血前检测孕产妇ABO与RhD血型的临床价值观察  

Clinical value of ABO and RhD blood groups detection in pregnant women before delivery and before blood transfusion

作　　者：毕汇文[1] 郑俊青[1] 李坚[2] 刘悦芹[1] Bi Huiwen;Zheng Junqing;Li Jian;Liu Yueqin(Jinan Maternal and Child Health Hospital,Jinan 250001,China（Bi HW,Zheng JQ,Liu YQ;Shandong Provincial Police General Hospital,Jinan 250002,China（Li J)

机构地区：[1]济南市妇幼保健院,250001 [2]山东省警官总医院,济南250002

出　　处：《国际医药卫生导报》2018年第21期3277-3279,共3页International Medicine and Health Guidance News

摘　　要：目的分析产前及输血前检测孕产妇ABO与RhD血型的临床价值.方法选择2017年3月至2018年3月于本院进行体检的孕产妇4213例.对所有孕产妇均进行不规则抗体筛查,并记录筛查结果,另检测不规则抗体阳性结果夫妻血型、不规则抗体特异性及血清效价.结果经筛查发现,不规则抗体阳性者占1.26%（53/4213）.在53例不规则抗体阳性结果孕产妇中,A型占15.09%,B型占24.53%,O型占52.83%,AB型占7.55%;RhD阳性占90.57%,其中抗E占比最高,为37.50%（18/48）.O型孕产妇与A型丈夫15例,其中血清抗A效价不低于128者占53.33%;O型孕产妇与B型丈夫11例,其中血清抗B效价不低于128者占27.27%;O型孕产妇与AB型丈夫2例,其中血清抗AB效价不低于128者占50%.结论在产前、输血前,对孕产妇进行不规则抗体、ABO与RhD血型检测能够为临床上确定母婴血型不配合、易流产或发生新生儿溶血病（Hemolytic disease of the newborn,HDN）提供依据.Objective To analyze the clinical value of ABO and RhD blood groups detection in pregnant women before delivery and before blood transfusion. Methods 4 213 pregnant women who underwent physical examination in our hospital from March 2017 to March 2018 were selected. All pregnant women were screened for irregular antibody, and the test results were recorded. The blood group, the specifcity of irregular antibody,serum tilter of couples with irregular antibody positive were detected. Results Among 4 213 pregnant women, there were 53 cases of irregular antibody positive （1.26%）, 15.09% of whom were type A, 24.53% of type B, 52.83% of type O, 7.55% of type AB; the positive rate of RhD was 98.11%, and the proportion of anti-E was the highest [37.50% （18/48）]. There were 15 cases of type O pregnant women and type A husbands, the proportion of serum anti-A tilter ≥128 was 53.33%; there were 11 cases of type O pregnant women and type B husbands, the proportion of serum anti-B tilter ≥128 was 27.27%; there were 2 cases of type O pregnant women and type AB husbands, the proportion of serum anti-AB tilter ≥ 128 was 50%. Conclusion Irregular antibody, ABO and RhD blood groups detection in pregnant women before delivery and before blood transfusion can be used to determine the mismatch of maternal and infant blood groups, easy abortion, hemolytic disease of the newborn （HDN）.

关 键 词：孕产妇 ABO血型 RHD血型 不规则抗体 

分 类 号：R714[医药卫生—妇产科学] R457.11[医药卫生—临床医学]