损及肾盂行锁边缝合法的中华田园犬实验研究  

Experimental animal study of injury and kidney pelvis line suture in Chinese rural dogs

作　　者：刘高 傅点[3] 程文[3] LIU Gao;FU Dian;CHENG Wen(Medical School of Nanjing University,Jiangsu Province,Nanjing 210002,China;Department of Urology,Suqian People′s Hospital of Nanjing Drum-Tower Hospital Group,Jiangsu Province,Suqian 223800,China;Department of Urology,Nanjing General Hospital of Nanjing Military Region,Jiangsu Province,Nanjing 210002,China)

机构地区：[1]南京大学医学院,江苏南京210002 [2]南京鼓楼医院集团宿迁市人民医院泌尿外科,江苏宿迁223800 [3]南京军区南京总医院泌尿外科,江苏南京210002

出　　处：《中国医药导报》2018年第32期9-12,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81572526)

摘　　要：目的探讨肾盂、肾实质及肾包膜全层连续锁边缝合法在肾肿瘤肾部分切除术后创面缝合中的效果。方法选择4只健康雄性中华田园犬,麻醉成功后按人类开放性肾部分切除术程序进行操作,对创面的肾盂黏膜、黏膜下层、肌层及肾膜层间行连续锁边缝合。观察手术时间、术中出血量、动脉阻断时间、术后恢复活动时间、围术期并发症发生情况。结果肾动脉阻断手术时间、局部阻断手术时间、肾动脉阻断时间、局部阻断时间分别为(39.00±2.16)、(37.50±4.30)、(10.25±2.50)、(8.45±1.81) min,肾动脉阻断肾部分切除及缝合术中出血量为(54.50±4.21) mL、局部阻断肾部分切除及缝合术中出血量为(57.50±9.58) mL。麻醉苏醒即可原地活动。次日予以进食,1周后恢复如常。结论本术式手术时间短、出血量少、恢复快,术后未出现大出血与漏尿等严重并发症,有效地预防与制止肾部分切除术后常见两大并发症,为其临床应用奠定了基础。Objective To investigate the effect of continuous suture of renal pelvis, renal parenchyma and renal capsule on wound suture after removal of renal pelvis tumor. Methods Four healthy male Chinese rural dogs were selected. After successful anesthesia, the operation was performed according to the human open kidney partial resection procedure. The sutures of the renal pelvis mucosa, submucosa, muscular layer and renal layer were sutured continuously. The operation time, intraoperative blood loss, arterial block time, postoperative recovery time, and perioperative complications were observed. Results The operation time of renal artery occlusion, local occlusion time, renal artery occlusion time and local occlusion time were （39.00±2.16）, （37.50±4.30）, （10.25±2.50）, （8.45±1.81） min, respectively. The amount of bleeding in the renal artery block partial nephrectomy and suture was （54.50±4.21） mL, and the amount of hemorrhage during local partial nephrectomy and suturing was （57.50±9.58） mL. After the anesthesia waken up, they could move in place. The next day, they were given food and returned to normal after a week. Conclusion The operation time is short, the amount of bleeding is small, the recovery is fast, and there are no serious complications such as major bleeding and urinary leakage after operation. It effectively prevents and eliminates two common complications after partial nephrectomy, which lays a foundation for its clinical application.

关 键 词：肾部分切除术 肾盂肿瘤 锁边缝合法 阻断 

分 类 号：R687.3[医药卫生—骨科学]