阴道分娩后卵巢静脉血栓一例  

Ovarian vein thrombosis after vaginal delivery： a case report

作　　者：王秋明[1] 武海英[1] 王焕萍[1] Wang Qiuming;Wu Haiying;Wang Huanping(Department of Obstetrics,Henan Provincial People＇s Hospital,Zhengzhou 450003,China)

机构地区：[1]河南省人民医院产科,郑州450003

出　　处：《中华围产医学杂志》2018年第11期777-779,共3页Chinese Journal of Perinatal Medicine

摘　　要：卵巢静脉血栓（ovarian vein thrombosis，OVT）是一种少见、隐匿且非常凶险的疾病，常发生于产后妇女，如不能及时发现可能导致严重后果。因此，早期诊断和治疗OVT非常重要。本文报道1例产妇阴道分娩后第3天出现发热伴左侧腰痛，行增强CT检查提示：左侧卵巢静脉广泛血栓形成，达肾静脉水平；血栓易感基因检测提示：纤溶酶原激活物抑制剂-1（rs587776796）基因型：4G／5G杂合突变，5，10-亚甲基四氢叶酸还原酶（rs1801133）基因型：C／T杂合突变。给予低分子肝素及利伐沙班，取得较好的治疗效果。Ovarian vein thrombosis （OVT） is a rare, insidious and dangerous disease mostly occurs in the postpartum period. Early diagnosis and timely treatment are very important and may avoid serious complications. Here we reported a woman who had a fever and left back pain three days after vaginal delivery. Enhanced CT suggested that thrombosis occurred in the left ovarian vein, and even the renal vein was involved. Thrombus susceptibility gene detection revealed that the plasminogen activator inhibitor-1 gene was 4G/5G heterozygous genotype and the 5,10- methylenetetra-hydrofolate reductase gene was C/T heterozygous genotype. Anticoagulant treatments with low-molecular-weight heparin and rivaroxaban were effective.

关 键 词：产褥期疾病 静脉血栓形成 卵巢 

分 类 号：R714.3[医药卫生—妇产科学] R711.75[医药卫生—临床医学]