复方黄栌口服液治疗急性病毒性黄疸型肝炎湿热蕴结证临床研究  

Clinical Study of Compound Common Smoketree Twig and Leaf Oral Liquid in Treating Acute Viral Jaundice Hepatitis with Syndrome of Intermingled Damp and Heat

作　　者：李彩虹 马俊杰[1] 高延玲[1] 苏峰[1] 刘芬[1] 刘建峰 张正臣[1] 姚德胜 LI Cai-hong;MA Jun-jie;GAO Yan-ling;SU Feng;LIU Fen;LIU Jian-feng;ZHANG Zheng-chen;YAO De-sheng(Xinxiang 371 Center Hospital of Henan,Xinxiang,Henan,China,453000)

机构地区：[1]中国人民解放军第371中心医院,河南新乡453000

出　　处：《河南中医》2018年第10期1527-1530,共4页Henan Traditional Chinese Medicine

基　　金：新乡市重点科技攻关项目(编号:ZG14012)

摘　　要：目的:观察复方黄栌口服液治疗急性病毒性黄疸型肝炎湿热蕴结证的临床疗效。方法:选取本院治疗的急性病毒性黄疸型肝炎湿热蕴结证患者200例,随机分为对照组和治疗组,每组100例。对照组给予保护肝功能、降低转氨酶等常规西药对症治疗,治疗组在对照组治疗的基础上加用复方黄栌口服液治疗。两组疗程均为4周,并于治疗后3个月进行随访。检测两组患者治疗前后总胆红素(total bilirubin,TBIL)、结合胆红素(Direct bilirubin,DBIL)、谷丙转氨酶(alanine transaminase,ALT)、谷草转氨酶(aspartateaminotransferase,AST)水平,并进行临床症状评分,观察治疗效果。结果:两组治疗后临床疗效比较,对照组有效率为76. 00%,治疗组有效率为90. 00%,治疗组优于对照组(P <0. 05),差异具有统计学意义;两组患者治疗后3个月随访,对照组有效率为80. 20%,治疗组有效率为94. 80%,治疗组优于对照组(P <0. 05),差异具有统计学意义;治疗后,治疗组与对照组TBIL、DBIL、ALT、AST水平比较,差异均具有统计学意义(P <0. 05);治疗后3个月随访,治疗组与对照组TBIL、DBIL、ALT、AST水平及并发症发生情况比较,差异均具有统计学意义(P <0. 05)。结论:复方黄栌口服液治疗急性病毒性黄疸型肝炎湿热蕴结证疗效显著,能够改善患者的黄疸症状及肝功能,缩短病程,减少并发症,远期疗效好。Objective： To observe the clinical curative effect of Compound Common Smoketree Twig and Leaf Oral Liquid on acute viral jaundice hepatitis with syndrome of intermingled damp and heat. Methods： Two hundred patients with acute viral jaundice hepatitis with syndrome of intermingled damp and heat who were treated in our hospital were randomly divided into the control group and the treatment group,with 100 cases in each group. The ones in the control group were given routine Western medicine symptomatic treatment,such as liver protection,enzyme reduction. The ones in the treatment group were given Compound Common Smoketree Twig and Leaf Oral Liquid on the basis of the treatment of the control group. The two groups were treated for 4 weeks and were followed up for 3 months after the treatment. The levels of total bilirubin（TBIL）,direct bilirubin（DBIL）,alanine transaminase（ALT） and aspartate aminotransferase（AST） were measured before and after the treatment,and the clinical symptoms were evaluated. Results： In terms of the clinical curative effect of the two groups after the treatment,the effective rate of the control group was 76. 00%,and that of the treatment group was 90. 00%,the treatment group was better than the control group（P〈0. 05）,the difference was statistically significant. The two groups were followed up for 3 months after treatment. The effective rate of the control group was 80. 20%,and that of the treatment group was 94. 80%,the treatment group was better than the control group（P〈0. 05）. After the treatment,the levels of TBIL,DBIL,ALT and AST in the treatment group were significantly different from those in the control group（P〈0. 05）,and all the differences between them had significance（P〈0. 05）. After 3 months＇ follow-up after the treatment,,the levels of TBIL,DBIL,ALT,AST and complications in the treatment group and the control group were significantly different（P〈0. 05）. Conclusion： Compound Common Smoketree Twig and Leaf Oral Liquid has a remar

关 键 词：急性病毒性黄疸型肝炎 复方黄栌口服液 湿热蕴结证 

分 类 号：R259.751[医药卫生—中西医结合]