108例肝炎肝硬化患者FibroScan检测值与舌象的相关性分析  

Correlation analysis of tongue manifestations and FibroScan value in 108 patients with post-hepatitic cirrhosis

作　　者：窦智丽 吴秀艳 王天芳 薛晓琳 赵丽红 李昕 李宁 Dou Zhili;Wu Xiuyan;Wang Tianfang;Xue Xiaolin;Zhao Lihong;Li Xin;Li Ning(Beijing University of Chinese Medicine,Beijing 100029,China;Dongzhimen Hospital of Beijing University of Chinese Medicine Beijing 100700,China)

机构地区：[1]北京中医药大学中医学院,北京100029 [2]北京中医药大学东直门医院

出　　处：《北京中医药大学学报》2018年第10期854-858,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)资助项目(No.2011CB505105);国家自然科学基金青年科学基金资助项目(No.81302915)~~

摘　　要：目的分析肝炎肝硬化患者的舌象与瞬时弹性成像技术(Fibro Scan)检测值(FS值)的相关性,为中医通过望舌判断病情严重程度提供客观依据。方法运用肝炎肝硬化临床信息采集表收集患者的一般病情资料、舌象、FS值等,并用Excel进行数据录入,将数据根据舌象有无出现分组,并运用SPSS 20. 0软件对患者临床信息、FS值及舌象进行描述性统计分析,采用t检验、卡方检验、秩和检验等。结果 (1)108例肝炎肝硬化患者,FS值最小值4. 1 k Pa,最大值75 k Pa,平均(24. 07±18. 43) k Pa,其中代偿期(16. 18±10. 06) k Pa,失代偿期(38. 03±21. 50) k Pa,2期比较差异有统计学意义(P <0. 01);(2)108例患者不同舌象FS值的比较发现:舌色上,红绛舌组FS值最高;舌形上,瘦舌组FS值最高;苔质上,燥苔组FS值最高;苔色上,黄苔组FS值最高。所有分组中,只有胖舌组、裂纹舌组以及燥苔组差异比较有统计学意义(P <0. 05),其余各组间差异比较无统计学意义。结论舌象表现为瘦舌、裂纹舌和燥苔患者的FS值较高,说明当肝炎肝硬化患者出现以上3种舌象时,病机主要以热证、阴虚、血虚和津伤为主,提示肝硬化病情越严重。由此可以看出,作为判断病情严重程度的FS值与舌象变化有一定的相关性。Objective To investigate the correlation of tongue manifestations and FibroScan value in patients with post-hepatitic cirrhosis and provide objective evaluation of illness severity and pathogenesis.Methods The clinical information extraction table of hepatitis cirrhosis was used to collect the general information of the patient＇s condition,the FS value of the tongue image and etc. The data were inputted into Excel,and grouped according to whether there was any tongue picture or not. SPSS 20. 0 software was used to analyze the clinical information of patients with descriptive statistical analysis,including t test,chi-square test,and rank sum test. Results In 108 patients with post-hepatitic cirrhosis,the minimum value of FS was 4. 10 kPa and the maximum value was 75. 00 kPa. The mean value was（ 24. 07 ± 18. 43） k Pa; compensatoed stage（ 16. 18 ± 10. 06） k Pa,decompensated stage（ 38. 03 ±21）. There was significant difference between the two stages（ P〈0. 05）. FS of the crimson tongue was highest in the color of tongue. In tongue shape,Fs of thin tongue was higher than other tongues. In tongue coating,dry and yellow coating were higher than others. Among all the groups,only the bulgy tongue group,the cracked tongue group and the dry fur group had significant differences（ P〈0. 05）,but there was no significant difference between other groups. Conclusion FS value appears to ke higher in the patients with thin tongue,fissured tongue and dry coating. It shows that the higher the FS value of heat syndrome,yin deficiency,blood deficiency and injury,the more serious the condition of liver cirrhosis is when the above three tongue signs appear in the patients with hepatitis and liver cirrhosis. This indicates that FS value has a certain correlation with tongue changes.

关 键 词：肝炎肝硬化 瞬时弹性成像技术 舌象 望诊 

分 类 号：R256.42[医药卫生—中医内科学]