婴幼儿铁缺乏症与脑发育障碍相关性研究  

Association between iron deficiency and brain developmental disorder in children

作　　者：傅晓燕 谢晓恬[2] FU Xiao-Yan;XIE Xiao-Tian(Department of Pediatrics,Shanghai Luodian Hospital,Shanghai 201908,China)

机构地区：[1]上海市罗店医院儿科,上海201908 [2]上海市同济医院儿科,上海200065

出　　处：《中国当代儿科杂志》2018年第11期964-967,共4页Chinese Journal of Contemporary Pediatrics

基　　金：上海市卫计委科研项目(WSJ1239);上海市先进适宜技术推广项目(2013SY073)

摘　　要：铁缺乏症(ID)是儿童期最为常见的微量元素缺乏症。胎儿晚期、新生儿和婴幼儿期是大脑发育的关键时期,这些阶段的铁缺乏可导致大脑发育的不可逆性损害,包括情感行为异常、认知功能下降和注意力缺陷等脑功能异常表现,并可能持续至成人阶段,必须引起足够的重视。该文就生命早期铁缺乏导致大脑发育障碍的主要机制以及干预措施等研究进展进行综述。Iron deficiency（ID） is the most common trace element deficiency in childhood. Recent studies have shown that late fetus period, neonatal period, and infancy are important periods for brain development, and ID during these periods may cause irreversible damage to brain development, including abnormal emotion and behavior, cognitive decline, and attention deficit, which may still be present in adulthood. Therefore, it should be taken seriously. This article summarizes the research advances in major mechanisms involved in brain developmental disorder due to ID in the early stage of life and related intervention measures.

关 键 词：铁缺乏症 神经发育 认知功能 行为异常 儿童 

分 类 号：R723.2[医药卫生—儿科] R742[医药卫生—临床医学]