192例输血不良反应的回顾性研究  

192 Cases of Adverse Events of Blood Transfusion:A Retrospective Study

作　　者：刘建辉[1] 陈文燕 贾桂丛[2] 陈莉[2] LIU Jianhui;CHEN Wenyan;JIA Guicong(Hebei General Hospital,Shijiazhuang,Hebei,050051,China)

机构地区：[1]河北省人民医院,河北石家庄050051 [2]河北省血液中心,河北石家庄050071

出　　处：《中国卫生质量管理》2018年第6期18-20,40,共4页Chinese Health Quality Management

基　　金：河北省2018年度医学科学研究重点课题(20180932)

摘　　要：目的对2017年上报的输血不良反应进行回顾性评估分级,为最终制定输血不良反应分类规范提供参考。方法汇总2017年石家庄市5家三级医院上报至河北省血液中心的192例输血不良反应,根据患者输血前后的临床表现及变化、相关实验室检查等数据对输血不良反应进行重新评估,从反应类型的肯定程度、反应的严重程度、反应与输血相关性3方面进行评估分级。结果上报的192例输血不良反应中,过敏性输血反应116例,非溶血性发热反应68例;肯定158例,基本肯定31例,疑似3例;不严重178例,严重12例,危及生命2例;反应与输血明确相关14例,很有可能相关162例,可能有关16例。结论将输血不良反应按肯定程度、严重程度、相关性程度进行分类,从深度和广度上进行分析讨论,提高了诊断的准确性和严谨性,在一定程度上避免了输血不良反应的漏报、误报,也为制定省级输血不良反应统一标准奠定了基础。Objective To retrospectively evaluate the adverse events of transfusions reported in 2017, and provide reference for the final formulation of classification criteria for adverse events of transfusion. Method A total of 192 cases of adverse blood transfusion events were reported from five tertiary hospitals in Shijiazhuang in Hebei Province in 2017. According to the clinical manifestations and changes of patients before and after transfusion, relevant laboratory tests data, the adverse events of transfusion were re evaluated. The affirmation degree of response type , severity of the reaction,reaction and transfusion correlation, were evaluated and graded. Result Among the 1.92 adverse events of transfusion, 116 cases of allergic transfusion reaction, 68 cases of non hemolytic febrile reaction; 158 cases were con firmed, 31 cases were basically affirmed, 3 cases were suspected; 178 cases were not serious, 12 cases were serious, 2 cases were life threatening; 14 cases were clearly related to reaction and blood transfusion, and 162 cases were likely to be related, and 16 cases may be related. Conclusion The adverse events of transfusion were classified according to the ＂affirmation degree＂, ＂severity degree＂ and ＂degree of relevance＂. The analysis and discussion from depth and breadth improved the accuracy and rigor of the diagnosis. To some extent, the adverse events of transfusion could be avoided. Missing reports and false positives also laid the foundation for the establishment of a unified standard for provincial blood transfusion adverse events.

关 键 词：输血不良反应 分类规范 回顾性研究 

分 类 号：R457.1[医药卫生—治疗学]