磺酸功能化胆碱催化合成14-芳基-14H-二苯并[a,j]氧杂蒽衍生物  

Synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives catalyzed by sulfonic acid functionalized choline

作　　者：王英磊[1,2] 杜朝军 叶红勇[1,2] 李入林 WANG Ying-lei;DU Chao-jun;YE Hong-yong;LI Ru-lin(School of Biological and Chemical Engineering,Nanyang Institute of Technology,Nanyang 473004,China;Henan Key Laboratory of Industrial Microbial Resources and Fermentation Technology,Nanyang 473004,China)

机构地区：[1]南阳理工学院生物与化学工程学院,河南南阳473004 [2]河南省工业微生物资源与发酵技术重点实验室,河南南阳473004

出　　处：《化学研究与应用》2018年第11期1830-1835,共6页Chemical Research and Application

基　　金：河南省科技攻关项目(182102310601)资助;河南省高等学校重点科研项目(17B150007)资助

摘　　要：以氯化胆碱为原料,制备了磺酸功能化胆碱催化剂,在水介质中催化芳香醛和2-萘酚反应合成了一系列14-芳基-14H-二苯并[a,j]氧杂蒽衍生物,产率达85～97%。该催化剂具有良好的生物相容性,易于分离和重复利用,符合绿色化学的发展理念。The sulfonic acid functionalized choline was prepared by using choline chloride as the raw material,which was applied as an efficient catalyst for the synthesis of a series of 14-aryl-14 H -dibenzo[ a,j ]xanthene derivatives via the condensation of aromatic aldehyde and 2-naphthol in aqueous media,with the yield of 85~97%.This catalyst possessed good biocompatibility,as well as easy separation and reutilization,which meet the development concept of green chemistry.

关 键 词：磺酸功能化胆碱 氧杂蒽 水相 循环使用 

分 类 号：O626[理学—有机化学]