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作 者:宋彩娟[1] 曲振宇[2] 李国伟[1] 韩同武[1] SONG Cai-juan;QU Zhen-yu;LI Guo-wei;HAN Tong-wu(Zhengzhou Center for Disease Control and Prevention,Zhengzhou,Henan 450042,China)
机构地区:[1]郑州市疾病预防控制中心,河南郑州450042 [2]漯河医学高等专科学校,河南漯河462002
出 处:《现代预防医学》2018年第22期4173-4175,共3页Modern Preventive Medicine
基 金:2017年河南省高等学校重点科研项目计划(17B310003)
摘 要:目的对郑州市2012-2017年所监测的急性迟缓性麻痹(Acute Flaccid Paralysis, AFP)病例进行流行病学特征分析,为提高医生AFP的诊断水平和AFP防控策略的制定提供依据。方法对AFP专病信息报告管理系统中2012-2017年郑州市16个市(区县)所报告的AFP病例进行分析。结果 2012-2017年这6年中郑州市共报告AFP病例226例,年平均发病率为2.91/10万,8月份报告病例最多,达32例;16个市区县中登封市报告病例数最多,达32例;有23个医院参与病例报告,其中报告最多是郑州市儿童医院(69例);病例主要集中于5岁以下人群,完成免疫者占总病例数的84.96%;实验室监测出PEV和NPEV阳性毒株;临床症状以发热和肌肉疼痛为主,治疗后仍有19.46%的患者有不同程度的残留麻痹。结论郑州市2012-2017年AFP病例年平均发病率整体上呈现出下降趋势,提示该市脊灰防治工作效果良好,但基层医院的诊断水平有待提高,治疗后仍有患者存在麻痹症状,需进行长期监测。Objective This study aimed to investigate and analyze the epidemiological characteristics of acute flaccid paralysis (AFP) cases in Zhengzhou City from 2012 to 2017, improve the ability of diagnosis of AFP for doctors and provide a scientific basis for disease prevention and control. Methods An epidemiological survey was carried out on AFP cases reported in 16 cities and counties of Zhengzhou city from 2012 to 2017, followed by statistical analysis of the data. Results A total of 226 AFP cases were reported in Zhengzhou city from 2012 to 2017: the average annual incidence is 2.91/10 million, most cases were reported in August, Dengfeng city was on the first position with 32 cases, the case report came from 23 hospitals, and the most of which was the Zhengzhou Children's Hospital (69 cases). The cases mainly occurred in people under 5 years old, the number of cases completed immunization of the poliomyelitis vaccine accounted for 84.96% of the total, PEV and NPEV positive strains were monitored in the laboratory, fever and muscle pain are the main clinical symptoms, and there are still different levels of residual paralysis existing in the patients after the treatment. Conclusion From 2012 to 2017, the annual incidence of AFP cases in Zhengzhou declined year by year. It shows that the effect of polio prevention and control work in this city is good, but the level of diagnosis in primary hospital needs to be improved. After the treatment, there are still paralyzed s,cmptoms in the patient and need to be monitored for a long time.
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