2018版中国《肺血栓栓塞症诊治与预防指南》解读之五：慢性血栓栓塞性肺动脉高压的诊治  

Interpretation of the guidelines on the diagnosis, management and prevention of pulmonary thromboembolism: diagnosis andtreatment of chronic thromboembolic pulmonary hypertension

作　　者：王静 张宇[2,3] 陶新曹 WANG Jing;ZHANG Yu;TAO Xin-cao(Beijing University Health Science Center,Beijing 100029,China)

机构地区：[1]北京大学医学部,北京100029 [2]中日友好医院呼吸与危重医学科 中日友好医院呼吸中心,北京100029 [3]首都医科大学,北京100007

出　　处：《中国实用内科杂志》2018年第11期1024-1026,共3页Chinese Journal of Practical Internal Medicine

基　　金：国家重点研发计划(2016YFC0905600);国家自然科学基金面上项目(81570049);国家自然科学基金面上项目(8187328);北京市自然科学基金资助项目(7182149)

摘　　要：慢性血栓栓塞性肺动脉高压(CTEPH)是急性肺血栓栓塞症(PTE)的远期并发症,属于第四大类肺动脉高压。肺动脉血栓内膜剥脱术(PEA)是CTEPH的首选治疗方法,不能行PEA或PEA术后残余肺动脉高压的患者可选择介入治疗和(或)药物治疗。与2001年《肺血栓栓塞症的诊断与治疗指南(草案)》相比,2018版《肺血栓栓塞症诊治与预防指南》增加了CTEPH的诊断和治疗。文章旨在详细解读新版指南中CTEPH的诊断策略和最新治疗方法,更好地指导临床实践。Chronic thromboembolic pulmonary hypertension （CTEPH） is the group IV pulmonary hypertension according to the WHO classification of pulmonary hypertension, and it＇s also a long-term complication of acute pulmonary thromboembolism （PTE）. Pulmonary thromboendarterectomy （PEA） is the first-choice treatment for CTEPH, and for the patients who can not receive PEA or who have remained pulmonary hypertension after PEA, intervention and/or drug treatment can be performed. Compared with the 2001 Guidelines for the Diagnosis and Treatment of Pulmonary ＂Ihromboembolism （Draft）, the Guidelines for the Diagnosis, Treatment and Prevention of Pulmonary Thromboembolism （2018） have been added the diagnosis and treatment of CTEPH. This article aims to give a detailed interpretation of diagnostic strategies and the latest treatments of CTEPH in the latest edition of guidelines.

关 键 词：慢性血栓栓塞性肺动脉高压 肺动脉血栓内膜剥脱术 球囊肺动脉成形术 肺动脉高压 

分 类 号：R543.2[医药卫生—心血管疾病]