中药洗浴方治疗新生儿黄疸效果及对EPO水平的影响  

Efficacy of traditional Chinese medicine bathing prescription on neonatal jaundice and EPO levels

作　　者：马圆圆[1] 冯伟伟[1] 苏婕 王宇军[1] 邹祥阳 阮为勇[1] MA Yuanyuan;FENG Weiwei;SU Jie;WANG Yujun;ZOU Xiangyang;RUAN Weiyong(Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Nanjing University of Chinese Medicine,NanJing 210028,Jiangsu,China;Nanjing University of Traditional Chinese Medicine,NanJing 210023,Jiangsu,China)

机构地区：[1]南京中医药大学附属中西医结合医院,江苏南京210028 [2]南京中医药大学,江苏南京210023

出　　处：《现代中西医结合杂志》2018年第35期3892-3894,3915,共4页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：江苏省中医药局科技项目(YB2015045)

摘　　要：目的观察中药洗浴方治疗新生儿黄疸的效果及对血清促红细胞生成素(EPO)的影响。方法将90例黄疸新生儿随机分为3组,西医治疗组30例予常规治疗,茵栀黄组在常规治疗基础上服用茵栀黄口服液,中药洗浴组在常规治疗基础上予中药洗浴,观察比较3组临床疗效及治疗前后血清EPO的变化。结果中药洗浴组、茵栀黄组临床总有效率均显著高于西医治疗组(P均<0. 05);中药洗浴组、茵栀黄组经皮黄疸值、治疗后血清总胆红素水平均显著低于西医治疗组(P均<0. 05),黄疸消退时间均显著短于西医治疗组(P均<0. 05)。3组治疗后EPO水平均较治疗前明显下降(P均<0. 05),3组间EPO水平比较差异无统计学意义(P均> 0. 05)。结论中药洗浴方治疗新生儿黄疸有良好的临床疗效,可明显降低血清EPO水平,且新生儿及家长容易接受。Objective It is to observe the curative effect of traditional Chinese medicine bathing prescription on neonatal jaundice and serum erythropoietin （EPO）. Methods 90 newborns with jaundice were randomly divided into three groups, 30 cases in the western medicine group were given conventional treatment, 30 cases in the Yinzhihuang group were given Yinzhihuang oral solution by oral administration on the base of conventional treatment, 30 cases in traditional Chinese medicine bathing group was given traditional Chinese medicine bath on the base of conventional treatment. The clinical effects and the changes of serum EPO before and after jaundice treatment were observed and compared in the three groups. Results The total effective rate in Chinese medicine bath group and Yinzhihuang group was higher, percutaneous jaundice value and the level of serum total bilirubin was lower, and jaundice fade time was shorter than those in western medicine group （ P 〈0.05）. The level of EPO of the three groups was significantly lower than that before treatment （ P 〈0.05）, the difference among the three groups was not significant （ P 〉0.05）. Conclusion Chinese herbal bath decoction has a good clinical effect on neonatal jaundice, it could significantly decrease the level of serum EPO and be easily accepted by the newborn parents.

关 键 词：新生儿黄疸 中药洗浴 茵栀黄口服液 促红细胞生成素 

分 类 号：R722[医药卫生—儿科]