金樱子HPLC指纹图谱研究  

Study on Fingerprint of Rosae Laevigatae Fructus

作　　者：胡莹[1,2] 吴啟南[2] HU Ying;WU Qi-nan(Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Nanjing University of Chinese Medicine,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学附属医院,江苏南京210029 [2]南京中医药大学,江苏省中药资源产业化协同中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心,江苏南京210023

出　　处：《中国中医药信息杂志》2018年第12期71-75,共5页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家科技支撑计划(2011BAI04B06);国家公益性行业专项(201407002);国家公共卫生行业专项(2014002);江苏高校优势学科建设工程资助项目(2014年)

摘　　要：目的建立金樱子指纹图谱,为提高金樱子质量标准奠定基础,为规范金樱子饮片市场及确保药材内在质量的均一性和稳定性提供较全面的质量控制手段。方法采用HPLC结合《中药色谱指纹图谱相似度评价系统(2012版)》对金樱子指纹图谱进行相似度评价并建立共有模式,采用SPSS19.0软件进行聚类分析。结果初步建立了金樱子HPLC指纹图谱,确定了10个不同产地金樱子指纹图谱的9个共有峰。结论本方法建立的HPLC指纹图谱可用于金樱子质量评价。Objective To establish the fingerprint of Rosae Laevigatae Fructus; To lay a foundation for improving the quality standard of Rosae Laevigatae Fructus; To provide a comprehensive quality control method for the market standardization of Rosae Laevigatae Fructus sample to ensure the quality of medicinal materials internal homogeneity and stability. Methods HPLC method and TCM Chromatogram Fingerprint Similarity Evaluation System （2012 edition） were used to evaluate the similarity and establish the common mode of Rosae Laevigatae Fructus, and the SPSS19.0 software was used for cluster analysis. Results The HPLC fingerprint of Rosae Laevigatae Fructus was established, and a total of 9 common peaks of Rosae Laevigatae Fructus from 10 different producing areas were marked. Conclusion The HPLC fingerprint established in this study can be used for the quality evaluation of Rosae Laevigatae Fructus.

关 键 词：金樱子 芦丁 高效液相色谱法 指纹图谱 聚类分析 

分 类 号：R284.1[医药卫生—中药学]