芪兰颗粒治疗肝硬化腹水80例疗效观察  

Clinical effect of Qilan granules in treatment of cirrhotic ascites:An analysis of 80 cases

作　　者：刘红虹[1] 赵平[1] 赵艳玲[1] 靳雪源[1] 程勇前[1] 闫涛[1] 卿松[1] 王建军[1] 吴亮 LIU Hong-hong;ZHAO Ping;ZHAO Yan-ling;JIN Xue-yuan;CHENG Yong-qian;YAN Tao;QING Song;WANG Jian-jun;WU Liang(302 Hospital of PLA,Beijing 100039,China)

机构地区：[1]中国人民解放军第302医院,北京100039

出　　处：《湖南中医杂志》2018年第10期1-3,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：中国人民解放军第302医院院内课题(编号:YNKT2014027)

摘　　要：目的:观察芪兰颗粒治疗气虚血瘀、水湿停滞型肝硬化腹水的临床疗效。方法:将符合诊断标准的肝硬化腹水患者80例随机分为2组各40例,对照组单纯采用利尿剂治疗,治疗组在对照组基础上加用芪兰颗粒治疗,疗程均为4周,比较2组临床疗效。结果:总有效率治疗组为90. 00%,对照组为75. 00%,2组比较,差异有统计学意义(P <0. 05);治疗后,治疗组白蛋白(ALB)、胆碱脂酶(CHE)水平上升,丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AGT)、总胆红素(TBi L)水平下降,与对照组比较,差异均有统计学意义(P <0. 05或P <0. 01)。结论:芪兰颗粒联合利尿剂治疗气虚血瘀、水湿停滞型肝硬化腹水较单用利尿剂更有效。Objective：To investigate the clinical effect of Qilan granules in the treatment of cirrhotic ascites with Qi deficiency with blood stasis and water-dampness stagnation. Methods：A total of 80 patients with cirrhotic ascites who met the diagnostic criteria were randomly divided into treatment group and control group,with 40 patients in each group. The patients in the control group were given diuretic alone,and those in the treatment group were given Qilan granules in addition to the treatment in the treatment group. The course of treatment was 4 weeks for both groups,and clinical outcome was compared between the two groups. Results：There was a significant difference in overall response rate between the treatment group and the control group（ 90. 00% vs 75. 00%,P〈0. 05）. After treatment,the treatment group had significant increases in albumin and cholinesterase and significant reductions in alanine aminotransferase,aspartate aminotransferase,and total bilirubin,and there were significant differences between the treatment group and the control group（ P〈0. 05 or P〈0. 01）. Conclusion：Compared with diuretic alone,Qilan granules combined with diuretic have a better clinical effect in the treatment of cirrhotic ascites with Qi deficiency with blood stasis and water-dampness stagnation.

关 键 词：肝硬化腹水 气虚血瘀证 水湿停滞证 芪兰颗粒 

分 类 号：R259.752[医药卫生—中西医结合]