金银花复方制剂对新城疫病毒感染雏鸡免疫器官抗体生成细胞数量的影响  

Effect of Honeysuckle Compound Preparation on the Number of Antibody-producing Cells in Immune Organs of Chickens Infected with Newcastle Disease Virus

作　　者：宋洋洋 王洪梅 李天琦[1,2] 于浩然 刘微[1,2] 葛铭 SONG Yang-yang;WANG Hong-mei;LI Tian-qi;YU Hao-ran;LIU Wei;GE Ming(College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China;Key Laboratoryfor Animal Diseases,Education Department of Heilongjiang,Harbin 150030,China)

机构地区：[1]东北农业大学动物医学学院,黑龙江哈尔滨150030 [2]黑龙江省教育厅动物普通疾病防治重点实验室,黑龙江哈尔滨150030

出　　处：《中国兽医杂志》2018年第8期54-57,61,共5页Chinese Journal of Veterinary Medicine

基　　金：国家重点研发计划资助(2017YFD0502200)

摘　　要：为探讨金银花复方制剂对新城疫病毒(NDV)感染雏鸡免疫器官抗体生成细胞数量的影响,本实验采用免疫酶组织化学法对NDV感染雏鸡免疫器官抗体生成细胞数量进行检测。结果显示,在NDV感染初期,NDV感染组雏鸡免疫器官抗体生成细胞数量与对照组雏鸡相比明显降低,表明NDV感染抑制了雏鸡的免疫功能;金银花复方制剂治疗组雏鸡免疫器官抗体生成细胞数量明显高于NDV感染组雏鸡,并且从第7天开始抗体生成细胞数量迅速恢复到对照组雏鸡的水平,表明金银花复方制剂提高了雏鸡的免疫功能。To investigate the effect of honeysuckle compound preparation on the number of antibody-producing cells in immuneorgans of chickens infected with Newcastle disease virus（NDV）. Immunohistochemistry were used to detective number of antibody-producing cells in immune organs of chickens. The results showed that the number of antibody - producing cells in Immune organs ofchickens infected with NDV were remarkably decreased remarkably in the early stage of infection comparing with that of the controlgroup, indicating that NDV infection could reduce the number of antibody-producing cells in immune organs of chickens and suppressimmune function. The number of antibody-producing cells in immune organs of chickens treated with honeysuckle compound preparationwere significantly higher than those in chickens infected with NDV and the number reached to the level of control group after 7 days. Ourresults indicated that honeysuckle compound preparation could protect antibody-producing cells in immune organs of chickens and en-hance the immune response level.

关 键 词：金银花复方制剂 新城疫病毒 雏鸡 免疫器官 抗体生成细胞 

分 类 号：S852.31[农业科学—基础兽医学]