盐酸艾司洛尔注射液在冠状动脉CTA检查中的临床应用  

Clinical Application of Esmolol Hydrochloride Injection in the Examination of Coronary Artery CTA

作　　者：刘更生[1] LIU Geng-sheng(Radiology department of Anfu county people＇s Hospital of Jiangxi,Anfu Jiangxi 343200,China)

机构地区：[1]江西省安福县人民医院放射科,江西安福343200

出　　处：《药品评价》2018年第22期44-45,52,共3页Drug Evaluation

基　　金：江西省卫生厅科技计划课题;编号:20143163

摘　　要：目的:研究分析在冠状动脉CTA检查中应用盐酸艾司洛尔注射液的临床价值。方法:选取2016年03月—2018年03月在我院接收治疗的98例冠状动脉检查患者为本次研究对象,均给予64排螺旋CT对患者的冠状动脉进行血管造影术(Computer tomography angiography,CTA)检查,通过采用抛硬币法随机分组原则,分为研究组和参照组,其中参照组49例,予以酒石酸美托洛尔,研究组49例,予以盐酸艾司洛尔注射液,比较两组图像质量情况、检查耗时以及心率控制情况。结果:研究组心率控制满意率为(95.92%),参照组心率控制满意率为(83.67%),差异不具有统计学意义(P>0.05);同时,研究组冠状动脉图像质量优良率为(97.96%),参照组冠状动脉图像优良率为(85.71%),差异不具有统计学意义(P>0.05);研究组平均检查耗时(5.23±0.17),短于参照组平均检查耗时(7.91±1.14),差异有统计学意义(P<0.05);研究组检查耗时≤6min患者所占比为48.98%(24/49),要高于参照组检查耗时≤6min患者所占比26.53%(13/49),差异具有统计学意义(P<0.05)。结论:对实施冠状动脉CTA检查患者,予以盐酸艾司洛尔注射液静脉注射,具有一定的应用价值。Objective： To study and analyze the clinical value of esmolol hydrochloride injection in coronary artery CTA examination.Methods： 98 patients receiving coronary artery examination in our hospital from March 2016 to March 2018 were selected as the study subjects. 64 slice spiral CT was performed on coronary artery angiography （CTAA）. According to the principle of coin toss, they were divided into the study group and the reference group. 49 cases in the reference group were treated with metoprolol tartrate, 49 cases in the study group were given esmolol hydrochloride injection. The image quality, inspection time and heart rate control of the two groups were compared. Results： The satisfaction rate of heart rate control in the study group was 95.92% and that in the reference group was 83.67%, with no significant difference （P〉0.05）. The excellent and good rate of coronary artery image quality in the study group was 97.96%, which were higher than that of the reference group （85.71%）, however, the difference was not significant （P〉0.05）. The average examination time of the study group was 5.23±0.17g, which was significantly shorter than that of the control group （7.91±1.14g, P〈0.05）. The proportion of patients with 6min in the study group was 48.98%, which was significantly higher than that in the control group （26.53% 13 / 49%, P〈0.05）.Conclusion： Intravenous injection of esmolol hydrochloride in patients undergoing coronary artery CTA examination is worthy of clinical application.

关 键 词：盐酸艾司洛尔注射液 冠状动脉 心率变化 质量 临床价值 

分 类 号：R445[医药卫生—影像医学与核医学]