赣南地区类风湿关节炎SDAI达标治疗的现状研究  

Study on treatment of rheumatoid arthritis SDAI in Gannan area

作　　者：陈琥[1] 李伟松[2] 谷晓晶[1] 李荣平[1] 郭迪斌[1] Cheng Hu;Li Weisong;Gu Xiaojin;Li Rongping;Guo Dibing(Rheumatology Department,First Affiliated Hospital of Gannan Medical University,Jiangxi,Ganzhou,341000,China;Pathology Department,First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi,341000,China)

机构地区：[1]赣南医学院第一附属医院风湿免疫科,江西赣州341000 [2]赣南医学院第一附属医院病理科,江西赣州341000

出　　处：《当代医学》2018年第34期99-101,共3页Contemporary Medicine

基　　金：赣州市指导性科技计划项目(GZ2017ZSF046)

摘　　要：目的本研究基于赣南地区RA患者人群,使用目标治疗的策略,获得本地区RA常规治疗效果及达标治疗效果的第一手资料,比较达标及经验的获益差别,指导临床治疗。方法收集50名赣南医学院第一附属医院风湿免疫科门诊及住院的类风湿关节炎患者,随机分为经验治疗组和达标治疗组,半年后所有患者行SDAI评分,使用SPSS 13.0软件分析两组患者的临床缓解率及总体疾病活动度水平。结果 25例达标治疗组RA患者的初始SDAI(23.12±6.65),治疗后(8.78±4.97);经验治疗组为初始SDAI(25.61±7.49),治疗后(13.86±4.96),达标治疗组SDAI评分下降更明显,差别有统计学意义(P<0.05)。结论类风湿关节炎的达标治疗组SDAI较经验治疗组整体评分更低,达标治疗策略方案大大改善了疾病活动,身体功能和生活质量,无需额外费用。Objective This study was based on the RA patients in the south of Jiangxi Province, using the strategy of target therapy to obtain the first hand information on the effect of conventional treatment and treatment of RA in the local area, and to compare the benefit difference between the standard and experience, and to guide the clinical treatment. Methods 50 patients with rheumatoid arthritis in the Department of Rheumatology and Immunology Department of First Affiliated Hospital of Gannan Medical College were randomly divided into the experience treatment group and the standard treatment group. After half a year, all the patients were scored by SDAI. The clinical remission rate and the overall degree of disease activity of the two groups were analyzed by SPSS13.0 software. Results： The initial SDAI （23.12±6.65） of the 25 patients with RA in the standard treatment group, （8.78±4.97） after treatment, and the initial SDAI （25.61±7.49） in the experience treatment group （13.86± 4.96）, and the decrease of the score in the treatment group were more obvious, and the difference was statistically significant. Conclusion： the SDAI in the treatment group for rheumatoid arthritis is lower than that in the experience group. The standard treatment strategy greatly improves the disease activity, the physical function and the quality of life without additional cost.

关 键 词：类风湿关节炎 SDAI 达标治疗 

分 类 号：R593.22[医药卫生—内科学]