短小芽孢杆菌BA06的比较基因组分析  

Comparative genome analysis of Bacillus pumilus BA06

作　　者：刘云山 田应明 李校[1] LIU Yun-Shan;TIAN Ying-Ming;LI Xiao(Sichuan Key Laboratory of Molecular Biology and Biotechnology,College of Life Sciences,Sichuan University,Chengdu 610065,China)

机构地区：[1]四川大学生命科学学院四川省分子生物与生物技术重点实验室,成都610065

出　　处：《四川大学学报（自然科学版）》2018年第6期1324-1330,共7页Journal of Sichuan University(Natural Science Edition)

基　　金：国家自然科学基金(31171204)

摘　　要：将短小芽孢杆菌BA06与其他18个短小芽孢杆菌菌株进行全基因组比较,鉴定出BA06基因组中有包括抗性岛、毒力岛、共生岛在内的12个基因组岛或噬菌体序列.基因家族分析鉴定出BA06有3个特异性基因家族,9个基因家族发生扩张,3个基因家族有所收缩.表明BA06在短小芽孢杆菌这一菌种中具有突出的抗药性与运动能力,并具有除皮革脱毛外更多的生物学特性.Compared whole genome of BA06 with other 18 B.pumilus strains and 12 Genomic islands or prophages were identified, including resistance island, pathogenicity island and symbiotic island. Gene family analysis indicated that BA06 has 3 peculiar gene families, 9 expansive gene families and 3 contractive gene families. Above all of these revealed that BA06 has outstanding drug resistance and moving ability in B.pumilus genus. BA06 possibly has more biological characteristics except dehairing activity.

关 键 词：短小芽孢杆菌 比较基因组学 基因组岛 基因家族 

分 类 号：Q814[生物学—生物工程]