中国不同区域20家三级综合医院外科大量输血后血常规及凝血检测频率与病死率的关联性分析  

Relevance between Frequency of the Blood Indicator Detection and the Case Fatality Rate in Massive Transfusion Surgical Patients

作　　者：庞建 马婷[2] 孙杨[2] 杨江存[2] PANG Jian,MA Ting,SUN Yang,YANG Jiang- cun(Weinan Blood Center,Shaanxi Weinan 714000, China; Shaanxi Provincial People＇ s Hospital, Xi＇ an 710068, China)

机构地区：[1]渭南市中心血站,陕西渭南714000 [2]陕西省人民医院,西安710068

出　　处：《现代检验医学杂志》2018年第6期73-76,共4页Journal of Modern Laboratory Medicine

摘　　要：目的了解外科大量输血时血细胞检测与凝血指标检测频率与病死率的相关性。方法对中国不同区域20家三级综合医院1 682例输血患者进行多中心回顾性分析,采用统一调研表格,统计分析红细胞悬液输注量<10U及≥10U情况下血细胞检测及凝血检测频次与病死率。结果 (1)不同输血量时(<10U组,≥10U组)血细胞检测及凝血检测频率差异均有统计学意义(P<0.05)。(2)外科不同病类红细胞悬液输注量≥10U血细胞检测及凝血检测1次以上与没有检测者差异均有统计学意义(Q_(smh)=8.286 7,P=0.004 0;Q_(smh)=20.383 9,P<0.000 1)。(3)外科大量输血患者血细胞检测及凝血指标检测频次与病死率均呈负相关(r=-0.900,P=0.037;r=-0.975,P=0.005)。结论外科大量输血时血细胞检测及凝血指标检测的及时性对降低患者死亡率具有一定的意义。Objective The observational study was conducted to define relevance between frequency of the hemocytography and the case fatality rate in massive transfusion surgical patients. Methods The frequency of the hemocytography and the case fatality rate were analyzed by multicenter retrospective study in 1 682 transfused patients from 20 tertiary comprehensive hospitals in different regions in China. The patients were transfused RBC with different volume in two groups which one was greater than or equal to 10 U,the other was lesser than 10 U. Results （1）There were significant differences in different amount of transfusion （〈10 U group, ≥10 U group） in the frequency of routine blood test and the coagulation tests （P〈 0.05）. （2）Obvious difference of routine blood test was seen between the frequency was 0 and the frequency was equal greater than 1 in massive transfusion surgical patients, so did the coagulation tests （Qsmh= 8. 286 7, P=0. 004 0; Qsmh = 20. 383 9, P 〈0. 000 1）. （3）The results showed a negative relation between frequency of the routine blood test and the case fatality rate, so did the coagulation tests （r= 0. 900, P=0. 037;r= 0. 975, P=0. 005）. Conclusion It is significant to the timeliness of hemocytography in massive transfusion surgical patients to reduce the case fatality rate.

关 键 词：大量输血 凝血指标 血细胞检测 病死率 

分 类 号：R457.1[医药卫生—治疗学]