高剂量率后装加外照射治疗气管金属支架植入后阻塞性肉芽增生——附四例分析  

High-dose-rate brachytherapy plus external beam radiotherapy:A utilized modality for tracheobronchial obstructive granulation hyperplasia induced by self-expandable metallic stents

作　　者：孙志强 于静萍 韦国桢 殷小伟 倪新初 王坚 聂斌 李栋庆 倪昕晔 刘茜 宋湘云 孙苏平 SUN Zhiqiang;YU Jingping;WEI Guozhen;YIN Xiaowei;NI Xinchu;WANG jian;NIE Bin;LI Dongqing;NI Xinye;LIU Xi;SONG Xiangyun;SUN Suping(The Affiliated Changzhou NO.2 people＇s Hospital of Nanfing Medical University,Changzhou 213000 China;Xuzhou Cancer Hospital)

机构地区：[1]南京医科大学附属常州第二人民医院,江苏常州213000 [2]徐州肿瘤医院

出　　处：《中国辐射卫生》2018年第4期376-380,共5页Chinese Journal of Radiological Health

摘　　要：目的观察高剂量率近距离后装加体外照射治疗气管、支气管良性狭窄金属支架植入后引起的气管阻塞性炎性肉芽增生的疗效。方法采用高剂量率近距离后装加体外照射治疗4例因金属支架植入后所导致的气管阻塞性炎性肉芽肿患者,根据临床症状及支气管镜的检查结果对治疗效果进行评估。结果 4例患者中有3例呼吸困难症状明显缓解,行支气管镜检查显示肉芽增生组织较治疗前显著退缩。结论后装治疗联合外照射可能会成为治疗气管阻塞性肉芽肿的新的有效方法。Objective To study the effect of high-dose-rate brachytherapy plus external beam radiotherapy（ HDRB plus EBR） for re-stricture induced by granulation hyperplasia after SEMS（ self-expandable metallic stents） implantation for benign tracheobronchial stricture. Methods 4 cases with re-stricture induced by granulation hyperplasia after SEMS implantation for benign tracheobronchial stricture were treated with high-dose-rate brachytherapy plus external beam radiotherapy,and the effect was evaluated according to the clinical symptoms alleviation and bronchoscopy result. Results 3 cases showed obvious dyspnea alleviation,and the granulation decreased obviously. Conclusion This study indicated that HDRB plus EBR might provide an effective therapeutic alternative for obstructive tracheal granulation hyperplasia.

关 键 词：肉芽增生 金属支架 近距离后装治疗 体外照射治疗 

分 类 号：R815[医药卫生—放射医学]