2011-2016年广东省出生缺陷儿治疗性引产情况  

Therapeutic induced labor of birth defects in Guangdong province,2011-2016

作　　者：袁晓兰[1] 徐昊立 YUAN Xiao Lan;XU Hao Li(Guangdong Women and Children＇s Health Care Hospital,Guangzhou 511442,China)

机构地区：[1]广东省妇幼保健院,广州511442

出　　处：《中国妇幼卫生杂志》2018年第5期11-15,共5页Chinese Journal of Women and Children Health

摘　　要：目的了解2011-2016年广东省出生缺陷儿治疗性引产情况。方法以2011-2016年在广东省出生缺陷监测体系内58家医院分娩的围产儿(孕28周至出生后7天)及孕产妇为研究对象,描述性分析广东省因出生缺陷而施行治疗性引产的胎儿的分布特征。结果 2011-2016年共监测出生缺陷儿51 574例,行治疗性引产者14 264例,占27.66%,<28周行治疗性引产者9575例,占67.22%,≥28周行治疗性引产者4689例,占32.87%。治疗性引产的胎儿,男性多于女性,性别比男∶女为1.46,其性别差异有统计学意义(χ~2=2471.81,P<0.001)。2011-2016年治疗性引产率呈下降趋势,经卡方趋势检验有统计学意义(χ~2=262.91,P<0.001)。<28周组中男性和女性胎儿选择引产的比例分别为92.52%和93.33%;≥28周组中男性和女性胎儿选择引产的比例分别为9.79%和13.55%。是否进行治疗性引产与患儿母亲的年龄、文化程度、家庭收入、产次、孕次及患儿性别、患儿孕周以及监测年度相关。2011-2016年进行治疗性引产的出生缺陷儿诊断依据以超声诊断为主,占77.99%,超声诊断的例次呈下降趋势,染色体诊断为依据例次总体呈上升趋势。结论广东省确诊为出生缺陷的患儿,进行治疗性引产的孕周提前;是否选择治疗性引产在一定程度上受非医学因素影响,进行治疗性引产的出生缺陷儿其诊断依据多元化。Objective To analyze the therapeutic induced laborof birth defects between 2011 and 2016 in Guangdong province.Method The study involved birth defects monitor records of mothers and infants between 2011 and 2016 from 58 monitoring network hospitals in Guangdong province. Descriptive statistics method was used to analyze the distribution characteristic of the infants who received therapeutic induced labor for birth defects. Result There were 51 574 cases of birth defects. Among them,14 264 mothers with birth defect infant received therapeutic induced labor,accounting for 27. 66%. Among 14264 mothers,9575 cases（ 67. 22%）received therapeutic induced labor at their gestational age 〈28 weeks. 4689 mothers（ 32. 87%） received therapeutic induced labor at their gestational ages ≥28 weeks. The number of male fetuses whose mother received therapeutic induced labor was more than that of female fetuses. The sex ratio was 1. 46. There was a statistical difference in the gender of birth defect infants（ χ^2= 2471. 81,P〈0. 001）. The trend test analysis showed that from 2011 to 2016,the therapeutic induced labor rates of the birth defects had a decreased trend（ χ^2= 262. 91,P〈0. 001）. Among the mothers who received therapeutic induced labor at their gestational age 28 weeks,92. 52% of their infants were male and 93. 33% were female. Among the mothers who received therapeutic induced labor at their gestational age ≥28 weeks,9. 79% of their infants were male and 13. 55% were female. Whether the mothers with birth defects to applied therapeutic induced labor was related to the mothers＇ age,cultural level,family income,delivery times,pregnant times,infant gender,gestational age and the monitor year. During 2011-2016,most of the birth defects were diagnosed by ultrasound（ 77. 99%）,however,the rates of ultrasonography showed a downward trend,and the rates of chromosome diagnosis emerged an upward trend. Conclusions The gestational age of the mothers with birth defect infants when they received therapeu

关 键 词：出生缺陷 治疗性引产 产前筛查 诊断依据 

分 类 号：R174[医药卫生—妇幼卫生保健]