2008-2012年中国肿瘤登记地区脑及神经系统肿瘤发病与死亡分析  

Analysis of incidence and mortality rates of brain and nervous system cancer in registration areas of China from 2008 to 2012

作　　者：查震球[1,2] 刘志荣[1] 郑荣寿[3] 陈万青[3] 叶冬青[2] ZHA Zhen-qiu;LIU Zhi-rong;ZHENG Rong-shou;CHEN Wan-qing;YE Dong-qing(Department of Non-communicable Chronic Disease Prevention,Anhui Provincial Center for Disease Control and Prevention,Heifei 230601,China;Department of Epidemiology and Biostatistics,School of Pnblic Health,Anhui Medical University,Anhui Province Key Laboratory of Major Autoimmune Diseases,Hefei 230032,China;National Central Cancer Registry,National Cancer Center,Beijing 100021,China)

机构地区：[1]安徽省疾病预防控制中心慢性非传染性疾病防治科,安徽合肥230601 [2]安徽医科大学公共卫生学院流行病与卫生统计学系重大自身免疫性疾病安徽省重点实验室,安徽合肥230032 [3]国家癌症中心全国肿瘤登记中心,北京100021

出　　处：《中华疾病控制杂志》2018年第11期1101-1105,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家重点研发计划(2016YFC1302605);安徽省重点研究与发展计划项目(1704a0802156)

摘　　要：目的描述中国肿瘤登记地区2008-2012年脑及神经系统肿瘤发病与死亡水平。方法对全国135个肿瘤登记处的数据进行汇总,计算脑及神经系统肿瘤的发病率与死亡率。结果 2008-2012年全国肿瘤登记地区脑及神经系统肿瘤发病率为6. 21/10万,中国人口标化率(以下简称中标率)为3. 93/10万,世界人口标化率(以下简称世标率)为3. 87/10万,占全部恶性肿瘤发病的2. 19%,位居全部恶性肿瘤发病的第11位。男性发病率为9. 45/10万(中标率为6. 31/10万),女性发病率2. 88/10万(中标率1. 72/10万)。城市和农村地区,脑及神经系统肿瘤发病率分别为7. 59/10万和4. 07/10万(发病中标率分别为4. 60/10万和2. 78/10万)。2008-2012年,全国肿瘤登记地区脑及神经系统肿瘤死亡率为2. 48/10万(中标率和世标率都为1. 40/10万),在各种恶性肿瘤死亡原因中排列第12位。男性的死亡率为3. 71/10万,女性为1. 21/10万。城市和农村地区脑及神经系统肿瘤死亡率分别为2. 91/10万和1. 81/10万(中标死亡率分别为1. 53/10万和1. 16/10万)。结论脑及神经系统肿瘤是危害中国居民主要恶性肿瘤之一,城市发病率高于农村,男性高于女性。应加强脑及神经系统肿瘤的预防与控制工作。Objective To describe the incidence and mortality rates of brain and nervous system cancer in 135 cancer registration areas of China from 2008 to 2012. Methods The pooled data from 135 cancer registration areas in China from 2008 to 2012 were collected, and the incidence and mortality rates of brain and nervous system cancer were calculated. Results The overall incidence rate of brain and nervous system cancer in 135 registration areas was 6.21/100 000, and age-standardized rate by Chinese standard population （ASR China） and age-standardized rate by Segi＇s world population（ASR world） were 3.93/100 000 and 3.87/100 000 respectively, accounting for 2.19% of whole cancer and being ranked as the eleventh common cancer in China. The crude cancer incidence of brain and nervous system and ASR China were 9.45/100 000 and 6. 31/100 000 for males compared with 2. 88/100 000 and 1.72/100 000 for females, respectively. The brain and nervous system cancer incidence and ASR China were 7.59/100 000 and 4. 60/100 000 in urban areas, while 4. 07/100 000 and 2.78/100 000 in rural areas, respectively. The crude mortality in China was 2.48/100 000 （male 3.71/100 000, female 1.21/100 000）, age-standardized mortality by Chinese standard population and by world standard population were both 1.40/100 000, and being ranked as the twelfth among the causes of death of various commnon cancer in China. The crude cancer mortality of brain and nervous system and ASR China were 2.91/100 000 and 1.53/100 000 inurban areas compared with 1.81/100 000 and 1.16/100 000 in rural areas, respectively. Conclusions Brain and nervous system cancer is one of the most common life-threatening cancers in China. The incidence rate of brain and nervous system cancer in urban areas is higher than that in rural areas of China, which is also higher in males than in females. The prevention and control for brain and nervous system cancer must be strengthened.

关 键 词：脑及神经系统肿瘤 发病率 死亡率 流行病学研究 

分 类 号：R181[医药卫生—流行病学] R73[医药卫生—公共卫生与预防医学]