我院2014—2017年药品不良反应报告回顾性分析  

Analysis of Adverse Drug Reaction Reports from 2014 to 2017 in Our Hospital

作　　者：王丹[1] 王颖丽[1] 段石顽 刘国一 梁乐[1] 陈敏 吕娟 郭未艳[1] 樊清清 王园姬 李亚美 WANG Dan;WANG Yingli;DUAN Shiwan;LIU Guoyi;LIANG Le;CHEN Min;LV Juan;GUO Weiyan;FAN Qingqing;WANG Yuanji;LI Yamei(Department of Pharmacy,the First Hospital of Xi′an,Shaanxi Xi′an 710002,China)

机构地区：[1]西安市第一医院药剂科,陕西西安710002

出　　处：《中国医药导刊》2018年第10期632-636,共5页Chinese Journal of Medicinal Guide

摘　　要：目的:分析我院2014—2017年药品不良反应(adverse drug reaction,ADR)发生的特点及相关因素,总结规律,借以促进临床合理用药。方法:采用回顾性分析方法,对我院2014—2017年上报至国家药品不良反应监测网的750例ADR报告进行分类统计与分析。结果:750例ADR中,年龄大于50岁的患者构成比最高,涉及的药品有213种,其中以抗感染药物诱发的ADR居多(33. 73%),静脉滴注给药是引发ADR的主要途径(77. 33%),临床表现以皮肤及其附件损害为主。结论:临床应重视ADR监测和报告工作,密切观察患者用药后的临床表现和反应,以促进临床合理用药,保障患者用药安全。Objective To analyze the characteristics and related factors of adverse drug reaction （ADR） reported from 2014 to 2017 in our hospita1 for promoting rational drug use. Methods ： A total of 750 ADR reports reported to the National Adverse Drug Reaction Monitoring Network in our hospital from 2014 to 2017 were analyzed retrospectively. Results ： Among 750 ADR cases, the patients over 50 years old had the highest incidence. The drugs that induced ADR totaled 213 kinds. 33.73% of ADR were induced by anti-infective drugs, and 77.33% were induced by intravenous drip administration. The major manifestation of ADR was the damage of skin and its appendants. Conclusion ： ADR monitoring and reporting should be emphasized, and should observe clinical manifestations and reaction in order to promote rational clinical drug use and to ensure patients′ safety.

关 键 词：药品不良反应 回顾性分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]