2型糖尿病患者踝肱指数与动力性平衡能力的相关性研究  

Relationship between ABI and dynamic balance in patients with type 2 diabetes mellitus

作　　者：司文[1] 牛春华[1] 牛嘉坪 陈新焰[1] 边青霞[1] 王蓓蓓[1] SIWen;NIUChunhua;NIU J iaping(Department of Endocrinology,Shengli Oil field Central Hospital,Dongying 257034,China)

机构地区：[1]胜利油田中心医院内分泌科,东营257034

出　　处：《中国糖尿病杂志》2018年第11期905-909,共5页Chinese Journal of Diabetes

摘　　要：目的探讨T2DM患者踝肱指数(ABI)与动力性平衡能力的相关性。方法选取2016年8月至2017年3月于我院内分泌科住院的T2DM患者257例,年龄30~80岁。根据ABI值分为无缺血组:0.9≤ABI<1.3,轻度缺血组:0.7≤ABI<0.9,中度缺血组:0.5≤ABI<0.7,重度缺血组:ABI<0.5。记录病史、卧位SBP,计算BMI,测定ABI、FPG、HbA_1c、股骨颈骨密度(CBMD)及动力性平衡指标:站起测试(CRT)、2.4m行走测试、走直线步态测试(TGT)。比较各组差异,分析ABI与动力性平衡能力的相关性。结果各组BMI、FPG、HbA_1c、卧位SBP、CBMD比较,差异无统计学意义。重度缺血组病程长于其他3组[20.0年(12.5,24.5)vs 11.0年(4.0,17.0)vs 8.5年(4.3,15.8)vs 10.0年(4.0,16.0),P<0.05],无缺血组、轻度缺血组、中度缺血组、重度缺血组CRT、2.4m行走测试逐渐延长[(9.36±4.12)vs(10.79±4.52)vs(16.21±4.95)vs(19.08±6.92)s,(3.33±1.48)vs(4.85±2.10)vs(7.92±2.69)vs(8.39±3.01)s,P<0.05],轻度缺血组与无缺血组CRT比较,差异无统计学意义。与无缺血组比较,重度缺血组TGT正常的比例降低(57.72%vs 22.72%,P<0.05)。Pearson相关性分析显示,ABI与CRT及2.4m行走测试呈负相关(r=-0.431、-0.383,P<0.01)。Logistic回归分析结果显示,年龄是TGT的影响因素。结论 T2DM患者ABI水平与行走稳定性呈负相关。Objective To investigate the correlation between ankle brachial index（ABI）and dynamic balance ability in T2DM patients. Methods From Aug 2016 to Mar 2017,257 patients with T2DM were admitted to our department of Endocrinology,aged 30~80 years.According to the ABI value,they were divided into non-ischemia group（0.9≤ABI1.3）,mild ischemia group（0.7≤ABI0.9）,moderate ischemia group（0.5≤ABI0.7）and severe ischemia group（ABI0.5）.Medical history,SBP in recumbent position,BMI,ABI,FPG,HbA_1c,bone mineral density of femoral neck（CBMD）and dynamic balance index were recorded.Stand up test（CRT）,2.4 m walk test and walking straight gait test（TGT）were performed.The relationship between ABI and dynamic balance ability was analyzed. Results There was no significant difference in BMI,FPG,HbA_1c,SBP and CBMD in each group.The duration of DM in severe ischemia group was longer than that in other 3 groups[20.0 years（12.5,24.5）vs 1.0 years（4.0,17.0）vs 8.5 years（4.3,15.8）vs 10.0 years（4.0,16.0）,P0.05].CRT and 2.4 m walk test were gradually prolonged from non-ischemia group,mild ischemia group,moderate ischemic to severe ischemia group [（9.36±4.12）vs（10.79±4.52）vs（16.21±4.95）vs（19.08±6.92）s,（3.33±1.48）vs（4.85±2.10）vs（7.92±2.69）vs（8.39±3.01）s,P0.05],There was no significant difference in CRT between mild ischemic group and non ischemic group.Compared with the ischemic group,the proportion of TGT in severe ischemia group was decreased（57.72%vs 22.72%,P0.05）.Pearson correlation analysis showed that ABI was correlated with CRT（r=-0.431,P0.01）and 2.4 m walking test（r=-0.383,P0.01）.Logistic regression analysis showed that age was the influencing factor of TGT. Conclusion There is a negative correlation between ABI level and walking stability in T2DM patients.

关 键 词：糖尿病 2型 踝肱指数 动力性平衡 

分 类 号：R587.1[医药卫生—内分泌]