体脂百分数与体质量指数对精液参数的影响  

Influence of body fat percentage and body mass index on semen parameters in adult males

作　　者：常亚丽 胡俊平[2] 杨媛[2] 赵小东[2] 林悦 高明霞[2] CHANG Ya-li;HU Jun-ping;YANG Yuan;ZHAO Xiao-dong;LIN Yue;GAO Ming-xia(School of Nursing;Special Hospital of Reproductive Medicine,Lanzhou University First Hospital / Key Laboratory for Reproductive Medicine and Embryos of Gansu Province,Lanzhou University,Lanzhou,Gansu 730000,China)

机构地区：[1]兰州大学护理学院,甘肃兰州730000 [2]兰州大学第一医院生殖医学专科医院/甘肃省生殖医学与胚胎重点实验室,甘肃兰州730000

出　　处：《中华男科学杂志》2018年第11期1005-1010,共6页National Journal of Andrology

摘　　要：目的:探讨成年男性体脂百分数(BF%)与体质量指数(BMI)对精液质量的影响。方法:随机选取男性不育患者125例,入选对象当天完成精液参数检查及BMI、BF%测定。以BMI≥28 kg/m^2作为肥胖标准,分为肥胖组50例、非肥胖组75例;以BF%> 25%作为肥胖标准,分为肥胖组69例、非肥胖组56例。比较两种评判肥胖标准中肥胖组与非肥胖组患者精液参数的差异,分析年龄、BMI、BF%与精液参数的相关性。结果:以BF%为评判标准,肥胖组患者精液量[(2. 94±1. 15) ml]、a+b级精子百分率[(33. 37±19. 80)%]、精子活率[(56. 31±22. 26)%]较非肥胖组[分别为(3. 51±1. 27) ml、(41. 87±15. 43)%、(64. 95±18. 22)%]显著降低(P <0. 05);以BMI为评判标准,肥胖组精液量[(2. 86±1. 11) ml]、a级精子百分率[(16. 33±13. 80)%]、a+b级精子百分率[(30. 10±18. 43)%]、精子活率[(53. 62±21. 56)%]较非肥胖组[分别为(3. 34±1. 26) ml、(25. 09±15. 06)%、(39. 80±17. 50)%、(62. 83±20. 47)%]显著降低(P <0. 05)。相关性分析结果显示年龄与精子活率呈负相关(r=-0. 20,<0. 05); BF%与精液量(r=-0. 21,P <0. 05)、a级精子百分率(r=-0. 21,P <0. 05)、a+b级精子百分率(r=-0. 18,P <0. 05)均呈负相关; BMI与精液量(r=-0. 26,P <0. 01)、a级精子百分率(r=-0. 23,P <0. 01)、a+b级精子百分率(r=-0. 18,P <0. 05)均呈负相关;进一步多因素分析显示,在排除年龄等因素后BF%与精液量、a+b级精子百分率均存在负性相关。结论:肥胖对男性不育患者的精液量、a级精子百分率、a+b级精子百分率、精子活率均存在影响; BF%可作为判断肥胖的纳入指标,检测结果可能更可靠。Objective： To explore the influence of body fat percentage（ BF%） and body mass index（ BMI） on the semen quality of adult males. Methods： A total of 125 randomly selected male infertility patients underwent examinations of semen quality,BMI and BF% on the day of enrollment. With BMI ≥28 kg/m^2 as the criterion of obesity,50 of the patients fell into the category of obesity and 75 into that of non-obesity,while with BF% 25% as the criterion,69 belonged to the obesity and 56 to the non-obesity type. We compared the semen parameters of the subjects between the obesity and non-obesity groups based on the two criteria and analyzed the correlation of semen quality with age,BF% and BMI. Results： With BF% as the criterion,the obesity patients,as compared with the non-obesity men,showed significantly lower semen volume（ [2. 94 ± 1. 15] vs [3. 51 ± 1. 27] ml,P〈0. 05）,percentage of grade a ＋ b sperm（ [33. 37 ± 19. 80]% vs [41. 87 ± 15. 43]%,P〈0. 05） and sperm motility（ [56. 31 ±22. 26]% vs [64. 95 ± 18. 22]%,P〈0. 05）. Similar results were observed with BMI as the criterion in the semen volume（ [2. 86± 1. 11] vs [3. 34 ± 1. 26] ml,P〈0. 05）,percentage of grade a sperm（ [16. 33 ± 13. 80]% vs [25. 09 ± 15. 06]%,P〈0. 05）,percentage of grade a ＋ b sperm（ [30. 10 ± 18. 43]% vs [39. 80 ± 17. 50]%,P〈0. 05） and sperm motility（ [53. 62 ±21. 56]% vs [62. 83 ± 20. 47]%,P〈0. 05）. Age was correlated negatively with sperm motility（ r =-0. 20,P〈0. 05）,BF%negatively with the semen volume（ r =-0. 21,P〈0. 05）,the percentage of grade a sperm（ r =-0. 21,P〈0. 05） and the percentage of grade a ＋ b sperm（ r =-0. 18,P〈0. 05）,and BMI negatively with the semen volume（ r =-0. 26,P〈0. 01）,percentage of grade a sperm（ r =-0. 23,P〈0. 01） and percentage of grade a ＋ b sperm（ r =-0. 18,P〈0. 05）. Further multivariate analysis also showed that BF% was negatively correlated with the semen volume and percentage of grade a ＋ b sperm after ex

关 键 词：男性不育 体脂百分数 体质量指数 肥胖 精液参数 

分 类 号：R589.2[医药卫生—内分泌] R698.2[医药卫生—内科学]