心周脂肪体积与心血管危险因素及能量消耗的相关性研究  

Associations Between Pericardial Adipose Tissue Volume and Cardiovascular Risk Factors and Energy Consumption

作　　者：李佳凝 孔维敏 高昕[1] 杨婷婷 冯纪涛[1] 王九荣 楼青青[1] LI Jia-ning;KONG Wei-min;GAO Xin;YANG Ting-ting;FENG Ji-tao;WANG Jiu-rong;LOU Qing-qing(Department of Cardiology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing（210028）,Jiangsu,China)

机构地区：[1]南京中医药大学附属中西医结合医院,江苏省南京市210028 [2]盐城市第一人民医院 [3]苏州市吴江区第一人民医院

出　　处：《中国循环杂志》2018年第11期1089-1093,共5页Chinese Circulation Journal

摘　　要：目的:探讨心周脂肪体积与心血管疾病危险因素及能量消耗的相关性。方法:本研究共纳入于2014-09至2015-12在南京中医药大学附属中西医结合医院疑似冠心病或已确诊冠心病需行冠状动脉计算机断层摄影术(CT)检查的成人住院患者152例,运用64排CT测量受试者心周脂肪体积,利用国际体力活动问卷计算能量消耗。分析心周脂肪体积与一般测量学、实验室指标及能量消耗的关系。结果:(1)心周脂肪体积与年龄、性别、收缩压、体重指数(BMI)、胰岛素抵抗(HMOA-IR)、空腹血糖(FPG)、高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)、总体力活动能量消耗、总中等强度体力活动能量消耗、总静坐能量消耗相关(P<0.05或P<0.001);(2)有胰岛素抵抗人群的心周脂肪体积明显大于无胰岛素抵抗的人群(P=0.001);(3)多元线性逐步回归分析显示,年龄、性别、BMI、总中等强度体力活动能量消耗与心周脂肪体积独立关联。结论:心周脂肪体积与年龄、性别、收缩压、BMI、总中等强度体力活动能量消耗有关。Objectives：The purpose of this study was to explore the relationship between the of pericardial adipose tissue （PAT） volume and cardiovascular disease risk factors and energy consumption. Methods：From September 2014 to December 2015, we enrolled 152 inpatients underwent coronary artery CT examination due to suspected coronary heart disease in the Hospital on Integration of Chinese and Western Medicine Affiliated to Nanjing University of Chinese Medicine. The volume of PAT was assessment by 64-slice CT, the energy consumption was assessment by the International Physical Activity Questionnaire. The clinical data, biochemical indexes, PAT volume were analyzed. Results ： （1） PAT volume was significantly correlated with age, gender, BMI, HOMA-IR, FPG, HDL-C, TG, total physical activity energy consumption, total middle intensity physical activity energy consumption, total energy consumption of sedentary （P〈0.05 or P〈0.001）; （2） PAT volume of patients with insulin resistance was significantly higher than those without insulin resistance; （3） Multiple regression analysis revealed that age, gender, BMI, total middle intensity physical activity energy consumption were independent predictors of PAT volume. Conclusions： Pericardial adipose tissue （PAT） volume is associated with age, gender, systolic blood pressure, BMI, total middle intensity physical activity energy consumption.

关 键 词：心周脂肪 CT 胰岛素抵抗 能量消耗 

分 类 号：R541.4[医药卫生—心血管疾病]