妊娠合并复杂先天性心脏病患者的围产结局分析  

Perinatal outcomes of 85 pregnant women with complex congenital heart disease

作　　者：李艳[1] 张孝艳[1] 杨蕾[1] 李月霞[2] 王小芳[3] LI Yan;ZHANG Xiaoyan;YANG Lei;LI Yuexia;WANG Xiaofang(Department of Obstetrics;Surgical Intensive Care Unit;Department of Cardiology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052,China)

机构地区：[1]郑州大学第一附属医院产科,郑州450052 [2]郑州大学第一附属医院重症医学科 [3]郑州大学第一附属医院心血管内科

出　　处：《临床心血管病杂志》2018年第11期1112-1115,共4页Journal of Clinical Cardiology

摘　　要：目的:探讨复杂先天性心脏病对孕妇和围产儿结局的影响。方法:选择2011-01-2017-01于郑州大学第一附属医院住院治疗的85例妊娠合并复杂先天性心脏病孕妇,孕前行心脏矫治手术的29例孕妇为A组,孕前未行心脏矫治手术的56例孕妇为B组,分析比较两组孕妇一般情况及围产结局。采用SPSS21.0统计软件进行统计学分析。结果:A组孕妇孕龄(36.17±6.90)周,经产妇12例;B组孕妇孕龄(28.65±6.36)周,经产妇7例。A组孕妇孕龄及经产妇比例明显高于B组,差异有统计学意义(P<0.05)。两组孕妇年龄、总住院天数及ICU住院天数比较差异无统计学意义。A组孕妇心功能评定、肺动脉高压(轻度、重度)和氧饱和结果均优于B组(P<0.05)。A组心力衰竭、母婴转入ICU、早产、新生儿窒息、小于孕龄儿和医源性流产的发生率均低于B组,差异有统计学意义(P<0.05)。结论:复杂先天性心脏病孕妇具有较高的围产期风险,可导致严重的母儿并发症。孕前行心脏矫治手术可改善孕妇心脏情况和母儿结局。Objective：To discuss the influence of complex congenital heart disease（CHD）on pregnant women and infants.Method：Selecting 85 cases of pregnant women complicated with complex CHD who were treated in the First Affiliated Hospital of Zhengzhou University from January 2011 to January 2017,29 pregnant women who had undergone cardiac surgery before conception as group A and 56 pregnant women who had not undergone cardiac surgery as group B,which all delivered in our center.The incidence of complications and perinatal outcomes were analyzed.All data were processed using statistical software SPSS21.0.Result：In group A,the mean gestational age（36.17±6.90）was higher than group B（28.65±6.36）.There was no significant difference in maternal age,total hospital days and ICU hospital days between the two groups.The results of pulmonary hypertension（mild,severe）and oxygen saturation were improved significantly in group C（P〈0.05）.Comparing to group B,complications of heart failure,maternal and infant admission to ICU,premature delivery,neonatal asphyxia,less than gestational age and iatrogenic abortion were decreased in group A（P〈0.05）.Conclusion：Pregnant women with complex CHD are at higher risk of perinatal adverse events.The outcomes of maternal and infant in women with cardiac surgery before conception could be improved.

关 键 词：妊娠 先天性心脏病 围产结局 

分 类 号：R541.1[医药卫生—心血管疾病]